DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3534 and Gykl1

DIOPT Version :9

Sequence 1:	NP_650582.1	Gene:	CG3534 / 42047	FlyBaseID:	FBgn0038463	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_599168.1	Gene:	Gykl1 / 291468	RGDID:	1305596	Length:	549	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	101/504 - (20%)
Similarity:	174/504 - (34%)	Gaps:	131/504 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 DRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQIDDSAFVVNRTPIWMDA 142
            ::|..|..|:|.:.||..:.|:..::.|.|.....|.|                    ..:|:|.
  Rat    73 EKLGQQSIDISNIKAIGVTNQRETTIVWDKFTGEPLYN--------------------AVVWLDL 117

  Fly   143 TTTKQCLEMEMAVGGKLNMVEL-TGSKCYERFTGPQIRKIYQ-----QRCHAYEEANR-ISLVSS 200
            .|......:..::....|.::: ||......|:..::..:.:     |:  |.|:... ...|.|
  Rat   118 RTQSTVENLNKSISASNNFIKIKTGLPISTYFSAVKLHWLIENVKNVQK--AIEDGRAFFGTVDS 180

  Fly   201 FI----SSLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECLNVCAPDLDKRLDIPV-------SPN 254
            ::    :....|.|...|.|:.|...|.:|....|.:|        |.:...||:       |.:
  Rat   181 WLIWCMTGGINGGVHCTDVSNASRTMLFNIHSLQWDEE--------LCEFFGIPMTILPRIRSSS 237

  Fly   255 SILGNVSPYFVERFSFSPDCKVAASTGDNPSALSGMLV---GSSWLTISMG-------------- 302
            .|.|.:....:|      ...::...||..:||.|.|.   |.:..|...|
  Rat   238 EIYGLMKSGVLE------GVPISGCLGDQSAALVGQLCLQDGQAKSTYGTGCFLLCNTGQKCVNS 296

  Fly   303 -----TSDTLMMSLKEPLNWE-EGHILCHPTETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFN 361
                 |:....|..:||:.:. ||.:        ...|.:    .|.::..:....:..|.:|..
  Rat   297 DHGLLTTVAYKMGREEPVYYALEGSV--------AIAGAV----VSWLKNNLQIIKSSSDIEKLA 349

  Fly   362 EYLDSTPRGNFGNMAVHFNDMEIIPKAQGILR--WNREMDPSSPDAARGVIKFSSPQIEIRALVE 424
            |.. .|..|.:           .:|...|:..  |    |||:.....|:.:|::......|.:|
  Rat   350 EKA-GTSYGCY-----------FVPAFSGLYAPYW----DPSARGIICGLTQFTNKFHIAFAALE 398

  Fly   425 GQMLHHRAVAEDLGYKFG-PETQILVTGGASVNKSILQTIADVFNAPVHIQDEGF--EAALLGAA 486
            ......|.:.:.:....| |.|.:.|.||.:.||.::|..||:...||.   :.|  |...||||
  Rat   399 AVCFQTREILDAMNSDCGIPLTHLQVDGGMTANKILMQLQADILCIPVM---KPFMPETTALGAA 460

  Fly   487 YRSAYALYLQEAGDGVTPLCYRDYILSLTSNKLSLV----CEPHKDSEE 531
            ..:.       |.:|:.       :.||....|:.|    .||..:.||
  Rat   461 MAAG-------AAEGIR-------VWSLDPKDLTGVQMEKFEPQINVEE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3534	NP_650582.1	FGGY_D-XK_euk	10..491	CDD:212660	91/458 (20%)
		PLN02669	11..546	CDD:178274	101/504 (20%)
		NBD_sugar-kinase_HSP70_actin	<447..545	CDD:302596	26/91 (29%)
Gykl1	NP_599168.1	glycerol_kin	11..513	CDD:273549	101/504 (20%)
Gykl1	NP_599168.1	FGGY_GK1-3_metazoa	11..513	CDD:212664	101/504 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910