DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3534 and SPCPJ732.02c

DIOPT Version :9

Sequence 1:	NP_650582.1	Gene:	CG3534 / 42047	FlyBaseID:	FBgn0038463	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001342982.1	Gene:	SPCPJ732.02c / 2539441	PomBaseID:	SPCPJ732.02c	Length:	555	Species:	Schizosaccharomyces pombe

Alignment Length:	569	Identity:	188/569 - (33%)
Similarity:	294/569 - (51%)	Gaps:	58/569 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLGFDLSTQKLKAVLLGSSLEVVAAAEVKFDTDLPEFRTTGGANAGSIKNEY--FVQPVMWVKAM 73
            |||.|||||:||.|::..||.|.....|.||.||.::.|..|.    .:|.|  |....||:.|:
pombe     2 FLGLDLSTQQLKGVVIDESLNVHQEVAVDFDRDLSDYNTIKGV----YRNGYEVFAPVCMWLDAI 62

  Fly    74 DIVLDRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQIDDSAFVVNRTPI 138
            |::.:|| ....|:|.:.||||:||||.|::..|.....|.:||::..|..|::  :.:...:|.
pombe    63 DLLFERL-KASVDVSKIQAISGAGQQHASVFLLKGSKKALNSLDAKSSLKQQLE--SLIHPTSPN 124

  Fly   139 WMDATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISLVSSFIS 203
            |.||:|||:|.|:|..:||...:.:|||||.:.|||||||::..:.....||...||:|||:|::
pombe   125 WQDASTTKECEELESCIGGAKALADLTGSKAHLRFTGPQIKRFRRLHPETYENTERIALVSNFLA 189

  Fly   204 SLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECL-----NVCAPDLDKRL-DIPVSPNSILGNVSP 262
            |:.|.:.||:|.||..||||.||:.:.:....|     |...|||..:| .:.::....||.:..
pombe   190 SVLLQTEAPLDISDVCGMNLWDIQNEKFDIRLLEEVAGNSKGPDLANKLGTVEINGAKHLGPIGK 254

  Fly   263 YFVERFSFSPDCKVAASTGDNPSA-LSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHILCHP 326
            |||:::.|||:|::...|||||:. ||..|.....:.:|:|||.|.:|:.:..:...|.|:..||
pombe   255 YFVKKYGFSPNCQIIPLTGDNPATILSLPLRPGKDVLLSLGTSTTALMATQNYVCSPEYHMFAHP 319

  Fly   327 TETEEFMGLLCFRNASLVREE----MNKKTTGGD---WDKFNEYL---DSTPRGNFGNMAVHFND 381
            .....:|.:||::|.||.||:    :|:|....|   ||:|||.:   :....|....:.:.:..
pombe   320 VTQNHYMVMLCYKNGSLAREQVRNTINEKYNVSDNTSWDRFNESILNPNIKGAGEKKQLGLFYPQ 384

  Fly   382 MEIIPKA---------QGILRWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQMLHHRAVAEDL 437
            .||:|..         ||...:..:.|..|.|         .|..:..|:||.|.|..|.....|
pombe   385 REILPAVGPGTWRFAIQGTELYQVDKDEESWD---------YPDEDASAIVESQNLDIRMRITPL 440

  Fly   438 GYKFGPETQILVTGGASVNKSILQTIADVFNAPVH-IQDEGFEAALLGAAYRSAYALYLQEAGDG 501
            ........::.|.||||.|::|:..|:.|....|: ::..|..|..:|.|.::|||:    .|.|
pombe   441 LTGIPQPDRVYVVGGASRNEAIVFKISQVLGCDVYRLKHGGSNACAVGGAIKAAYAM----NGKG 501

  Fly   502 VTPLCYRDYILSL--TSNKLSLVC-EPHKDSEEIYA---PMLQRYREMA 544
            .|   :.:|:...  .|.|:.|:. :|...:.|.|.   |.|::..::|
pombe   502 FT---FEEYVNKSWDESKKIELIMNKPSAQTYEEYGKLLPFLKKAEDIA 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3534	NP_650582.1	FGGY_D-XK_euk	10..491	CDD:212660	172/508 (34%)
		PLN02669	11..546	CDD:178274	188/569 (33%)
		NBD_sugar-kinase_HSP70_actin	<447..545	CDD:302596	30/105 (29%)
SPCPJ732.02c	NP_001342982.1	FGGY_D-XK_euk	1..495	CDD:212660	172/508 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1328
eggNOG	1	0.900	-	-		E1_COG1070
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I731
OMA	1	1.010	-	-		QHG56396
OrthoFinder	1	1.000	-	-		FOG0004391
OrthoInspector	1	1.000	-	-		otm47265
orthoMCL	1	0.900	-	-		OOG6_104017
Panther	1	1.100	-	-	LDO	PTHR10196
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1675
SonicParanoid	1	1.000	-	-		X3110
TreeFam	1	0.960	-	-
	13	12.860