DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3534 and AgaP_AGAP007581

DIOPT Version :9

Sequence 1:	NP_650582.1	Gene:	CG3534 / 42047	FlyBaseID:	FBgn0038463	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_308293.4	Gene:	AgaP_AGAP007581 / 1269648	VectorBaseID:	AGAP007581	Length:	540	Species:	Anopheles gambiae

Alignment Length:	474	Identity:	104/474 - (21%)
Similarity:	179/474 - (37%)	Gaps:	108/474 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 MWVKAMDIVLDRLVMQQADL--STVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQ--IDD 128
            :|...:.::  |...:.|:|  ..:|.::.:.|::....|:::......|..:.|.|.|.  :.|
Mosquito    59 LWTSVLQVI--RQATEDANLKIEQLACLAIATQRNSFTCWNRNTGQVYHNFITWKDLRADQLVKD 121

  Fly   129 SAFVVNRTPIWMDATTTKQCLEMEMAVGGKLNMVE-----LTGSKCYERFTGPQIRK----IYQQ 184
                      |.::.|.: .|:...:|   |:.|.     |.||..  :...|||..    :.|.
Mosquito   122 ----------WNESFTLR-LLKFGASV---LHFVTRSKRFLAGSVI--KLMNPQITLRLAWVLQN 170

  Fly   185 RCHAYEEANRISLVSSFISSLFL----------GSVAPI-DFSDGSGMNLLDIRKKNWSKECLNV 238
            .....|:....|::...|.|..|          ..|..| |.::.:...:.|...:.|:...||:
Mosquito   171 NPSVQEDLKHGSVLYGTIDSWLLYRLRQGTDLTKQVEHISDVTNCTSTGIYDPFGQEWAGWALNL 235

  Fly   239 CAPDLDKRLDIPVSPNSI-LGNVSPYFVERFSFSPDCKVAASTGDNPSALSGMLV---GSSWLTI 299
            .:  :.|.|...|..||. .|:|....:     ....|:|||..|..::|.|...   |.  :.|
Mosquito   236 FS--IKKELLPKVVDNSYDFGHVHETLL-----GARIKIAASVSDQAASLWGNCCFERGD--VKI 291

  Fly   300 SMGTSDTLMMSLKEPLNWEEGHILCHPTETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFN-EY 363
            :|||...|.::                      .|..|..:...:...:..|..||.....: .|
Mosquito   292 TMGTGSFLNVN----------------------TGTKCLASVHGLYPLIGYKLQGGAGSPPDIIY 334

  Fly   364 L---DSTPRGNFGNMAVH---FND------MEI-IPKAQGIL---RWNREMDPSSPDAAR----G 408
            |   .|...|:....|::   |:|      |.: :|.:.|:|   .::....|...|.|.    |
Mosquito   335 LMEGSSNDTGSIIEWALNVGLFDDPAASAAMALSVPNSDGVLFVPAFSGLGPPIRDDTAGSGFIG 399

  Fly   409 VIKFSSPQIEIRALVEG-----QMLHHRAVAEDLGYKFGPETQILVTGGASVNKSILQTIADVFN 468
            :...:..:..:|||:|.     .:|:..|:.| .|:.|   |.|.|.||.|.|..|.||:||:..
Mosquito   400 IKPSTRKEHMVRALLESLAFRVALLYDCALRE-TGFSF---TCIRVDGGVSKNDFICQTLADLTG 460

  Fly   469 APVHIQDEGFEAALLGAAY 487
            ..|. :.|..:::.|||.|
Mosquito   461 IEVE-RGEVADSSALGAMY 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3534	NP_650582.1	FGGY_D-XK_euk	10..491	CDD:212660	104/474 (22%)
		PLN02669	11..546	CDD:178274	104/474 (22%)
		NBD_sugar-kinase_HSP70_actin	<447..545	CDD:302596	17/41 (41%)
AgaP_AGAP007581	XP_308293.4	GlpK	7..530	CDD:223628	104/474 (22%)
AgaP_AGAP007581	XP_308293.4	FGGY_GK5_metazoa	8..527	CDD:212665	104/474 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910