DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3534 and xylb

DIOPT Version :9

Sequence 1:	NP_650582.1	Gene:	CG3534 / 42047	FlyBaseID:	FBgn0038463	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_017950252.1	Gene:	xylb / 100486367	XenbaseID:	XB-GENE-981856	Length:	557	Species:	Xenopus tropicalis

Alignment Length:	541	Identity:	237/541 - (43%)
Similarity:	347/541 - (64%)	Gaps:	23/541 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PPKQLKRTFLGFDLSTQKLKAVLLGSSLEVVAAAEVKFDTDLPEFRTTGGANAGSIKNEYFVQPV 67
            |.|..:..:||......:||.:.:...|:||....::||.|||||.|.||.:....|.......:
Frog    24 PKKDYRALYLGAYKDIAQLKVIAINEGLQVVLEDNIQFDRDLPEFGTQGGIHTHRDKLTVTSPVL 88

  Fly    68 MWVKAMDIVLDRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQIDDSAFV 132
            |||||:||:||||.....:...|.|:|||||||||:||.....:.|::|:::..||:.: ::.|.
Frog    89 MWVKALDIILDRLKSSGFNFGKVRALSGSGQQHGSVYWKNGARDQLRHLNADLPLHSLL-EACFS 152

  Fly   133 VNRTPIWMDATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISL 197
            |..:|||||::|:.:|..:|.||||...:..:|||:.||||||.||.|::.|:...|.:..||||
Frog   153 VADSPIWMDSSTSAKCHHLEEAVGGPQELANITGSRAYERFTGNQIAKMFHQKPEIYLQTERISL 217

  Fly   198 VSSFISSLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECLNVCAPDLDKRLDIPVSPNSILGNVSP 262
            ||||.:|||||..||||:|||||||||:|.:|.||:.||:.|||:|.:||...|..||:||:|||
Frog   218 VSSFAASLFLGDYAPIDYSDGSGMNLLNISEKTWSEICLDTCAPNLKERLGSVVPSNSVLGSVSP 282

  Fly   263 YFVERFSFSPDCKVAASTGDNPSALSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHILCHPT 327
            |:.:|:.||.:|::.|.|||||::|:||.:....:.:|:||||||.:.:::|....||||.|:|.
Frog   283 YYADRYGFSRECRIVAFTGDNPASLAGMRLQQGDIAVSLGTSDTLFLWIQDPTPALEGHIFCNPV 347

  Fly   328 ETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFNEYLDSTPRGNFGNMAVHFNDMEIIPKAQGIL 392
            :.:::|.||||:|.||:||.:..:...|.|:.|::.|.|||.||.||:..:|..|||.|:|.|:.
Frog   348 QHQDYMALLCFKNGSLMRERIRDECASGSWEIFSQALASTPPGNSGNVGFYFEAMEITPQAVGVH 412

  Fly   393 RWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQMLHHRAVAEDLGYKFGPETQILVTGGASVNK 457
            |:|.:        :|.|.:|.. .:|||||||||.:..|..||.||||..|:|:||.|||||.|:
Frog   413 RFNAD--------SRKVSEFPK-DVEIRALVEGQFMAKRIHAERLGYKIMPQTRILATGGASSNQ 468

  Fly   458 SILQTIADVFNAPVHIQDEGFEAALLGAAYRSAYALYLQ-EAGDGVTPLCYRDYILSLTSNKLSL 521
            .|||.::|||||||:..... .:|.|||||::|:.|.:: ...:|:.|         ...:||::
Frog   469 DILQVLSDVFNAPVYTIATA-NSACLGAAYQAAHGLAIEASVSEGLKP---------TEGHKLAV 523

  Fly   522 VCEPHKDSEEIYAPMLQRYRE 542
            .  |...::::|..:|:||.|
Frog   524 T--PRPGADKVYQALLKRYAE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3534	NP_650582.1	FGGY_D-XK_euk	10..491	CDD:212660	223/480 (46%)
		PLN02669	11..546	CDD:178274	235/533 (44%)
		NBD_sugar-kinase_HSP70_actin	<447..545	CDD:302596	36/97 (37%)
xylb	XP_017950252.1	FGGY_D-XK_euk	31..501	CDD:212660	223/480 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	181	1.000	Domainoid score	I3423
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3746
Inparanoid	1	1.050	449	1.000	Inparanoid score	I1581
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D335934at33208
OrthoFinder	1	1.000	-	-		FOG0004391
OrthoInspector	1	1.000	-	-		otm48579
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060