DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment EMC2A and AT5G28220

DIOPT Version :9

Sequence 1:	NP_001262652.1	Gene:	EMC2A / 42046	FlyBaseID:	FBgn0038462	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_198174.2	Gene:	AT5G28220 / 832898	AraportID:	AT5G28220	Length:	316	Species:	Arabidopsis thaliana

Alignment Length:	258	Identity:	97/258 - (37%)
Similarity:	143/258 - (55%)	Gaps:	16/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TW------REETGRHSEEVVQLWVAVLEDKVHKT--GNERHLILEQVIIAALDTARFDIATKCTK 75
            ||      |....|.||:|::...::|.|:..::  |.:...:.|||.|||:|.....:|..|.|
plant    37 TWEYLCLVRNLKVRRSEKVLKHGSSILNDQKKRSALGPDEWTLNEQVAIAAMDCQCLGVAQSCIK 101

  Fly    76 QLSLEFPGSLRVMKFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLEAIK 140
            .|..:||||.||.:.:|:..||...:.||:|...:::..:..:.|..||::||.||.|:...||:
plant   102 ALQTKFPGSKRVGRLEALLLEAKGLWGEAEEAYASLLEDNPLDQAIHKRRVAISKALGKPSIAIE 166

  Fly   141 ELNEYLKKFMSDQEAWHELCNMYLAEGEFGKAAFCMEEVLLHNPHSHLIHQRLAEIRYTMGGVEN 205
            .||:||:.||:|.:||.||..:||:...:.:||||.||::|..|...|.|...||:.||:|||||
plant   167 LLNKYLELFMADHDAWRELAELYLSLQMYKQAAFCYEELILSQPTVPLYHLAYAEVLYTIGGVEN 231

  Fly   206 MESARTYYSQALKL-NPHNLRALYGIYLCCN---HLDNSRAVSSK----RKELQKLSQWALEQ 260
            :.|||.||:..:.| ...|.|||.||.||.:   .|...|....|    ..||..|:..|:|:
plant   232 IISARKYYAATVDLTGGKNTRALLGICLCASAIAQLSKGRNKEDKDATAAPELHSLAAAAVEK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC2A	NP_001262652.1	TPR repeat	86..113	CDD:276809	8/26 (31%)
		TPR_11	154..221	CDD:290150	31/67 (46%)
		TPR repeat	154..181	CDD:276809	12/26 (46%)
		TPR repeat	186..219	CDD:276809	16/32 (50%)
AT5G28220	NP_198174.2	PGA_TPR_OMP	51..>185	CDD:274868	48/133 (36%)
		TPR repeat	115..139	CDD:276809	6/23 (26%)
		TPR repeat	144..174	CDD:276809	14/29 (48%)
		TPR repeat	179..206	CDD:276809	12/26 (46%)
		TPR repeat	213..239	CDD:276809	14/25 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1416
eggNOG	1	0.900	-	-		E1_KOG3060
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8785
Inparanoid	1	1.050	150	1.000	Inparanoid score	I1716
OMA	1	1.010	-	-		QHG55498
OrthoDB	1	1.010	-	-		D956854at2759
OrthoFinder	1	1.000	-	-		FOG0003504
OrthoInspector	1	1.000	-	-		mtm1182
orthoMCL	1	0.900	-	-		OOG6_102350
Panther	1	1.100	-	-	O	PTHR12760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2876
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840