DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EMC2A and AT3G04830

DIOPT Version :9

Sequence 1:	NP_001262652.1	Gene:	EMC2A / 42046	FlyBaseID:	FBgn0038462	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_850995.1	Gene:	AT3G04830 / 819643	AraportID:	AT3G04830	Length:	303	Species:	Arabidopsis thaliana

Alignment Length:	266	Identity:	94/266 - (35%)
Similarity:	148/266 - (55%)	Gaps:	12/266 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RHSEEVVQLWVAVLED--KVHKTGNERHLILEQVIIAALDTARFDIATKCTKQLSLEFPGSLRVM 88
            |.||.|::..:::|.|  |....|.:...:.|||.|||:|.....:|..|.|.|..:||.|.||.
plant    37 RRSEIVLKHGLSILNDSGKRSALGPDEWTLYEQVAIAAMDCQSLGVAQNCIKVLKKKFPESKRVG 101

  Fly    89 KFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLEAIKELNEYLKKFMSDQ 153
            |.:|:..||...::||::...:::..:..:....|||:|:.||:|:...||:.||:||:.||:|.
plant   102 KLEALLLEAKGMWEEAEKAYTSLLEDNPLDQVIHKRKVAMAKAQGKSSLAIEHLNKYLEVFMADH 166

  Fly   154 EAWHELCNMYLAEGEFGKAAFCMEEVLLHNPHSHLIHQRLAEIRYTMGGVENMESARTYYSQALK 218
            :||.||..:|::...:.:||||.||::|..|...|.|...|::.||:||:||:.:||.||:..:.
plant   167 DAWRELAEIYVSLQMYKQAAFCYEELILTQPTLPLYHLAYADVLYTIGGLENLIAARKYYAATID 231

  Fly   219 L-NPHNLRALYGIYLCCN---HLDNSRAVSSK---RKELQKLSQWALEQLLTKQTIVPLE---AA 273
            | ...:.|||.||.||.:   .:...|....|   ..|||.|:..|||:...::....|.   :|
plant   232 LTGGKSTRALLGICLCGSAIAQISKGRNKEDKDMAAPELQSLAATALEREYKQKAPAKLNLLTSA 296

  Fly   274 FGNLEI 279
            ..||:|
plant   297 LRNLKI 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EMC2A	NP_001262652.1	TPR repeat	86..113	CDD:276809	8/26 (31%)
		TPR_11	154..221	CDD:290150	27/67 (40%)
		TPR repeat	154..181	CDD:276809	11/26 (42%)
		TPR repeat	186..219	CDD:276809	13/32 (41%)
AT3G04830	NP_850995.1	TPR repeat	102..126	CDD:276809	6/23 (26%)
		TPR repeat	131..161	CDD:276809	13/29 (45%)
		TPR repeat	166..193	CDD:276809	11/26 (42%)
		TPR repeat	200..226	CDD:276809	11/25 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1416
eggNOG	1	0.900	-	-		E1_KOG3060
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8785
Inparanoid	1	1.050	150	1.000	Inparanoid score	I1716
OMA	1	1.010	-	-		QHG55498
OrthoDB	1	1.010	-	-		D956854at2759
OrthoFinder	1	1.000	-	-		FOG0003504
OrthoInspector	1	1.000	-	-		mtm1182
orthoMCL	1	0.900	-	-		OOG6_102350
Panther	1	1.100	-	-	LDO	PTHR12760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2876
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840