Protein Alignment EMC2A and emc2

DIOPT Version :10

• Sequence 1: NP_650581.1
• Gene: EMC2A / 42046
• FlyBaseID: FBgn0038462
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_001011398.1
• Gene: emc2 / 496871
• XenbaseID: XB-GENE-484487
• Length: 297
• Species: Xenopus tropicalis
• Alignment Length: 259
• Identity: 127/259 - (49%)
• Similarity: 187/259 - (72%)
• Gaps: 1/259 - (0%)

  Fly     4 DYEKMSWSDVRDQFRTWREETGRHSEEVVQLWVAVLEDKVHKTGNERHLILEQVIIAALDTARFD 68
            |...::|.|:||:.:|||||..|:||.|:::...::.:...|.|::..:|.|||:|||||..|.|
 Frog     6 DLYDVTWEDMRDKMKTWREENYRNSEHVIEVGEELINEHASKLGDDIWIIYEQVMIAALDCGRDD 70

  Fly    69 IATKCTKQLSLEFPGSLRVMKFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARG 133
            ||..|.::|..:||||.||.:...:|:||:|:||:|.::.|.|:..|.||.|.|||||||.||:|
 Frog    71 IAMSCLQELRRQFPGSHRVKRLTGLRFEAMERYDDALQIYDRILQDDPTNTAARKRKIAIRKAQG 135

  Fly   134 RRLEAIKELNEYLKKFMSDQEAWHELCNMYLAEGEFGKAAFCMEEVLLHNPHSHLIHQRLAEIRY 198
            |..|||:||||||::|:.||||||||..:|:.|.::.|||||:||::|.|||:|..:|:.||::|
 Frog   136 RNAEAIRELNEYLEQFVGDQEAWHELAELYINELDYAKAAFCLEELILTNPHNHFYYQQFAEVKY 200

  Fly   199 TMGGVENMESARTYYSQALKLNPHNLRALYGIYLCCNHL-DNSRAVSSKRKELQKLSQWALEQL 261
            |.||:||:|.:|.|:|||||||.||:|||:|:|:...|: .|.:|.:..:|:..|.:.||..|:
 Frog   201 TQGGLENLELSRKYFSQALKLNNHNMRALFGLYISSVHIASNPKASAKMKKDNVKYATWATSQI 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EMC2A	NP_650581.1	TPR repeat	86..113	CDD:276809	11/26 (42%)
		BepA	92..223	CDD:443813	75/130 (58%)
		TPR repeat	154..181	CDD:276809	15/26 (58%)
		TPR repeat	186..219	CDD:276809	17/32 (53%)
emc2	NP_001011398.1	Spy	55..>242	CDD:443119	104/186 (56%)
		TPR 1. /evidence=ECO:0000255	87..120		12/32 (38%)
		TPR repeat	120..150	CDD:276809	22/29 (76%)
		TPR 2. /evidence=ECO:0000255	155..188		19/32 (59%)
		TPR repeat	155..182	CDD:276809	16/26 (62%)
		TPR repeat	188..221	CDD:276809	17/32 (53%)
		TPR 3. /evidence=ECO:0000255	192..225		19/32 (59%)