Protein Alignment EMC2A and emc2

DIOPT Version :10

• Sequence 1: NP_650581.1
• Gene: EMC2A / 42046
• FlyBaseID: FBgn0038462
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: NP_998709.1
• Gene: emc2 / 407073
• ZFINID: ZDB-GENE-040625-82
• Length: 297
• Species: Danio rerio
• Alignment Length: 255
• Identity: 123/255 - (48%)
• Similarity: 187/255 - (73%)
• Gaps: 1/255 - (0%)

  Fly     8 MSWSDVRDQFRTWREETGRHSEEVVQLWVAVLEDKVHKTGNERHLILEQVIIAALDTARFDIATK 72
            ::|.::||:.|.||||..|:||::|.:...::.:...|.|::..:|.|||:|||||.:|.|:|..
Zfish    10 VTWEEMRDKLRKWREENYRNSEQIVDVGEELINEHASKLGDDIWIIYEQVMIAALDCSRDDLAWS 74

  Fly    73 CTKQLSLEFPGSLRVMKFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLE 137
            |.::|..:||.|.||.:...||.||||:||:|:::.|:|:..|.||.|.|||||.||:|:|:..|
Zfish    75 CLQELKRQFPDSHRVKRLAGMRLEALERYDDANKLYDSILQDDPTNTAARKRKICILRAQGKSSE 139

  Fly   138 AIKELNEYLKKFMSDQEAWHELCNMYLAEGEFGKAAFCMEEVLLHNPHSHLIHQRLAEIRYTMGG 202
            ||:||||||::|:.||||||||..:|:.|.::.|||||:||:::.|||:||..::.||::||.||
Zfish   140 AIRELNEYLEQFVGDQEAWHELSELYINEHDYAKAAFCLEELMMTNPHNHLYCEQYAEVKYTQGG 204

  Fly   203 VENMESARTYYSQALKLNPHNLRALYGIYLCCNHLDNSRAVSSK-RKELQKLSQWALEQL 261
            :||:|.||.|::||||||..|:|||:|:|:..:|:..|..||:| :|:..|.:.||..|:
Zfish   205 LENLELARKYFAQALKLNNRNMRALFGLYMSASHIAASPKVSAKVKKDNVKYAAWAAAQI 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EMC2A	NP_650581.1	TPR repeat	86..113	CDD:276809	13/26 (50%)
		BepA	92..223	CDD:443813	74/130 (57%)
		TPR repeat	154..181	CDD:276809	15/26 (58%)
		TPR repeat	186..219	CDD:276809	17/32 (53%)
emc2	NP_998709.1	Spy	55..>235	CDD:443119	99/179 (55%)
		TPR 1. /evidence=ECO:0000255	87..120		14/32 (44%)
		TPR repeat	87..115	CDD:276809	13/27 (48%)
		TPR repeat	120..150	CDD:276809	20/29 (69%)
		TPR 2. /evidence=ECO:0000255	155..188		18/32 (56%)
		TPR repeat	155..182	CDD:276809	16/26 (62%)
		TPR repeat	188..221	CDD:276809	17/32 (53%)
		TPR 3. /evidence=ECO:0000255	192..225		18/32 (56%)