DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AhcyL2 and SAHH2

DIOPT Version :9

Sequence 1:	NP_996221.1	Gene:	AhcyL2 / 42043	FlyBaseID:	FBgn0015011	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_189023.1	Gene:	SAHH2 / 821964	AraportID:	AT3G23810	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	477	Identity:	219/477 - (45%)
Similarity:	299/477 - (62%)	Gaps:	47/477 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SAGGTDFCVKSISKSAFGRREIEIAESEMPGIMTLRKRAKDEKPLKGANIVGCTHVNAQSAVLIE 126
            ::.|.::.||.:|::.|||.|||:||.||||:::........:|||||.|.|..|:..|:|||||
plant     8 TSSGREYKVKDMSQADFGRLEIELAEVEMPGLVSCVTEFGPSQPLKGARITGSLHMTIQTAVLIE 72

  Fly   127 TLVQLGATVRWAACNIYSTQNAVAAALAEAGIPIFAWRGETEEEFWWCLDRAI-YSDGWQPNLIL 190
            ||..|||.|||.:|||:|||:..|||:|.....:|||:|||.:|:|||.:||: :..|..|:||:
plant    73 TLTALGAEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCTERALDWGPGGGPDLIV 137

  Fly   191 DDGGDATHLM-----------------------------------------LKKYPDYFKAIRGI 214
            |||||||.|:                                         .|||....:.:.|:
plant   138 DDGGDATLLIHEGVKAEEIFAKNGTFPDPTSTDNPEFQIVLSIIKDGLQVDPKKYHKMKERLVGV 202

  Fly   215 VEESVTGVHRLYMLSKGGKLTVPAINVNDSVTKNKFDTFYTCRDSILDSLKRTTDIMFGGKQVVI 279
            .||:.|||.|||.:.:.|.|..|||||||||||:|||..|.||.|:.|.|.|.||:|..||..||
plant   203 SEETTTGVKRLYQMQETGALLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVAVI 267

  Fly   280 CGYGDVGKGCAQSLKGQGCIVYVTEVDPICALQAAMDGFRVVRLNEVIRTVDVVVTATGNKNVIT 344
            |||||||||||.::|..|..|.|||:||||||||.|:|.:|:.|.:|:...|:..|.||||::|.
plant   268 CGYGDVGKGCAAAMKTAGARVIVTEIDPICALQALMEGLQVLTLEDVVSEADIFCTTTGNKDIIM 332

  Fly   345 RDHMNRMKNGCILCNMGHSCSEIDVNGLHT-PELTWERVRSQVDHIRWPDGRM-IILLAEGRLVN 407
            .|||.:|||..|:||:||..:|||:.||.| |.:....::.|.|...:||... ||:||||||:|
plant   333 VDHMRKMKNNAIVCNIGHFDNEIDMLGLETYPGVKRITIKPQTDRWVFPDTNSGIIVLAEGRLMN 397

  Fly   408 LSCST-ISSFVVSVASSTQALALIELFS--APGRYKSDVYLLPKKMDEYVASLHLATFDAHLTEL 469
            |.|:| ..|||:|.:.:.|.:|.:||::  :.|:|:..||:|||.:||.||:|||....|.||:|
plant   398 LGCATGHPSFVMSCSFTNQVIAQLELWNEKSSGKYEKKVYVLPKHLDEKVAALHLGKLGARLTKL 462

  Fly   470 TDEQSKFMGLNKAGPFKANYYR 491
            |.:||.::.:...||:|..:||
plant   463 TKDQSDYVSIPVEGPYKPVHYR 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AhcyL2	NP_996221.1	PRK05476	63..486	CDD:235488	216/469 (46%)
AhcyL2	NP_996221.1	AdoHcyase	67..491	CDD:283003	216/470 (46%)
SAHH2	NP_189023.1	PLN02494	9..485	CDD:178111	219/476 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0499
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D371693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23420
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880