Protein Alignment abd-A and NKX6-2

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_796374.2
• Gene: NKX6-2 / 84504
• HGNCID: 19321
• Length: 277
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 71/281 - (25%)
• Similarity: 111/281 - (39%)
• Gaps: 76/281 - (27%)

  Fly   219 LNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTG 283
            ::.|.||              |...::|..||..:.|...:.::||         .|.|.|||
Human     1 MDTNRPG--------------AFVLSSAPLAALHNMAEMKTSLFPY---------ALQGPAGF-- 40

  Fly   284 LEDKSCSRYTDTVMNSYQSMSVPA--SASAQFAQFYQHATA--AASAVSAASAGAIG----VDSL 340
                                ..||  ...||......|..:  ....|.||..|.:|    ::.|
Human    41 --------------------KAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGL 85

  Fly   341 GNACTQPASGVMPGAGGAGGAG----IADLPRYP---WMTLTDWMGSPFE--RVV----CGDFNG 392
            .:     ::||..|...|...|    :|:||..|   |..:.  .|:|:.  |:.    .|....
Human    86 AS-----SAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVV--QGAPWRDPRLAGPAPAGGVLD 143

  Fly   393 PNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKEL 457
            .:| .::..|.|::..|...|||.|....||....|..:|::|.:||.|:|:||||||.|.:|.
Human   144 KDG-KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR- 206

  Fly   458 RAVKEINEQARRDREEQEKMK 478
            .||:..:.:.::| .:.||:|
Human   207 HAVEMASAKKKQD-SDAEKLK 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/51 (45%)
		Abdominal-A	456..478	CDD:289192	5/21 (24%)
NKX6-2	NP_796374.2	Repressor domain. /evidence=ECO:0000250|UniProtKB:D3Z4R4	89..142		14/54 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..155		3/23 (13%)
		Homeobox	151..204	CDD:306543	23/52 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910