DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and LHX5

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_071758.1	Gene:	LHX5 / 64211	HGNCID:	14216	Length:	402	Species:	Homo sapiens

Alignment Length:	145	Identity:	40/145 - (27%)
Similarity:	56/145 - (38%)	Gaps:	9/145 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 NGCPRRRGRQTYTRFQTLE-LEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLK--K 455
            |...:|||.:|..:.:.|| |:..|......||..|.::|....|..|.|::||||||.|.:  |
Human   175 NSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMK 239

  Fly   456 ELRAV----KEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQH--QQQQ 514
            :|.|:    .......||.|....::...|.:.|.........|..............|  ..|.
Human   240 QLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQA 304

  Fly   515 QQPQDHHSIIAHNPG 529
            |.|.|...:.|..||
Human   305 QSPADSSFLAASGPG 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	19/52 (37%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	5/25 (20%)
LHX5	NP_071758.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753
		LIM2_Lhx1_Lhx5	64..119	CDD:188761
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..186		4/10 (40%)
		Homeobox	183..237	CDD:395001	19/53 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	298..402		8/22 (36%)
		PHA03378	<301..>392	CDD:223065	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910