DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and hoxa3a

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_571609.1	Gene:	hoxa3a / 58049	ZFINID:	ZDB-GENE-000823-3	Length:	411	Species:	Danio rerio

Alignment Length:	359	Identity:	81/359 - (22%)
Similarity:	118/359 - (32%)	Gaps:	153/359 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 SPVSSSSPFQQ----HHPQVQQQHLNHQQQQHLHHQQQQHHH----QYSSLSAALQLQQQQHHIS 169
            |.:.|..|:|.    .:...|||:|     |.||.:.:.|..    |...:||.|....:...:.
Zfish    10 SAIYSGLPYQSANGLGYDASQQQYL-----QALHAESEYHRPACSLQSPGISAGLHTSNEMSEVC 69

  Fly   170 KLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNS--PGSASASAS 232
                          ||:                       :|:.:.....:||.  |.:.|..:|
Zfish    70 --------------QQI-----------------------NGTQATVTDTSDNKQPPTAPSGPSS 97

  Fly   233 ASAASSVAAAAAAAAAAASSSFAIPTSK-MYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTV 296
            .|:.:.:....:||......|....|.| ::|::.....:            .:.||||
Zfish    98 PSSLNQIPNIDSAAKNPVHVSPTPSTRKHIFPWMKESRQN------------TKQKSCS------ 144

  Fly   297 MNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGA 361
                                                 .|.|:|.......|     ||:..:
Zfish   145 -------------------------------------IISVESCAGRQKSP-----PGSAAS--- 164

  Fly   362 GIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRR 426
                                                 :|.|..||..|.:|||||||||.||.|.
Zfish   165 -------------------------------------KRARTAYTSAQLVELEKEFHFNRYLCRP 192

  Fly   427 RRIEIAHALCLTERQIKIWFQNRRMKLKKELRAV 460
            ||:|:|:.|.||||||||||||||||.||:.:.:
Zfish   193 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGL 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	37/51 (73%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	0/5 (0%)
hoxa3a	NP_571609.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..126		10/46 (22%)
		Antp-type hexapeptide	127..132		1/4 (25%)
		Homeobox	168..220	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	223..250		0/4 (0%)
		DUF4074	347..409	CDD:290032
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910