DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and dmbx1b

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001017625.1	Gene:	dmbx1b / 550288	ZFINID:	ZDB-GENE-050417-97	Length:	369	Species:	Danio rerio

Alignment Length:	253	Identity:	58/253 - (22%)
Similarity:	91/253 - (35%)	Gaps:	92/253 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 HGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIG 336
            |.|::|              |:...|||..:|   .:...|.||..|||.....:|.|.:.....
Zfish     3 HYGVNG--------------YSLHAMNSLSAM---YNLHQQAAQHAQHAPDYRPSVHALTLAERL 50

  Fly   337 VDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRG 401
            .|.:..|                        ||         ||...:             :||.
Zfish    51 ADIILEA------------------------RY---------GSQHRK-------------QRRS 69

  Fly   402 RQTYTRFQTLELEKEFHFNHY--LTRRRRIEIAHALC--LTERQIKIWFQNRRMKLKK------- 455
            |..:|..|...|||.|...||  :..|.|:    |:|  |.|.::::||:|||.|.:|
Zfish    70 RTAFTAQQLEALEKTFQKTHYPDVVMRERL----AMCTNLPEARVQVWFKNRRAKFRKKQRSLQK 130

  Fly   456 -ELRAVKEINEQARRD--REEQEKMKAQ-----------ETMKSAQQNKQVQQQQQQQ 499
             :|:.:||...:..:|  :||...::||           .:..|.:.|::|.....:|
Zfish   131 EQLQRLKEAGTEGAQDEGKEEAPPVEAQAPPSPLDGRGLTSAPSCELNEEVNVTSPEQ 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	21/55 (38%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	6/23 (26%)
dmbx1b	NP_001017625.1	Homeobox	69..122	CDD:278475	21/56 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..253		12/65 (18%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	346..359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910