Protein Alignment abd-A and PAX6

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001355839.1
• Gene: PAX6 / 5080
• HGNCID: 8620
• Length: 503
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 76/404 - (18%)
• Similarity: 129/404 - (31%)
• Gaps: 152/404 - (37%)

  Fly   146 QQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSS-CSPSPSA 209
            |..|.:....|:|.::::.....::|.|.::...|   :..|...||.|:    ||. |:
Human    31 QSQHAEQGGRSSAAEIKRAVAGANRLPALSLTCGG---RTCLWLKPSPGS----DSHVCT----- 83

  Fly   210 SGSSSLH---------RSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYV 265
            .|.|.::         |.|.|            |....:...|.:.|.....|..:       .|
Human    84 GGHSGVNQLGGVFVNGRPLPD------------STRQKIVELAHSGARPCDISRIL-------QV 129

  Fly   266 SNHPSSHGGLSGMAGFTGLEDKSCSRYTDT-------VMNSYQSMSVPASASAQFAQFYQHATA- 322
            ||               |...|...||.:|       :..|...::.|...| :.||:.:...:
Human   130 SN---------------GCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVS-KIAQYKRECPSI 178

  Fly   323 ---------------------AASAVS------AASAGAIGVDSLGNACTQPASGVMPGAGGAGG 360
                                 :.|:::      |:....:|.|.:.:...     ::.|..|:.|
Human   179 FAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLR-----MLNGQTGSWG 238

  Fly   361 AGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRG------------------------ 401
            .      |..|...|...|.|.:          :||.::.|
Human   239 T------RPGWYPGTSVPGQPTQ----------DGCQQQEGGGENTNSISSNGEDSDEAQMRLQL 287

  Fly   402 -------RQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRA 459
                   |.::|:.|...|||||...||.....|..:|..:.|.|.:|::||.|||.|.::|
Human   288 KRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRRE--- 349

  Fly   460 VKEINEQARRDREE 473
                 |:.|..|.:
Human   350 -----EKLRNQRRQ 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	21/51 (41%)
		Abdominal-A	456..478	CDD:289192	4/18 (22%)
PAX6	NP_001355839.1	PAX	85..209	CDD:128645	23/158 (15%)
		Homeobox	295..348	CDD:395001	21/52 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910