DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and Hoxb7

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001017480.1	Gene:	Hoxb7 / 497985	RGDID:	1559918	Length:	219	Species:	Rattus norvegicus

Alignment Length:	210	Identity:	91/210 - (43%)
Similarity:	105/210 - (50%)	Gaps:	37/210 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 EDKSCSRYTDTVMNSY-QSMSVPASASAQFAQFYQHATAAASAVSAASAG-AIGVDSLGNACT-- 345
            |..||:..::.....| .....|.|||.|.........|..||.....|| .:...|....|.
  Rat    28 EQTSCAFASNPQRPGYGAGPGAPFSASVQGLYSGGGGMAGQSAAGVYEAGYGLEPSSFNMHCAPF 92

  Fly   346 -QPASGVMPG----AGGAGGAGIADLPR------YPWMTLTDWMGSPFERVVCGDFNGPNGCPRR 399
             |..|||.||    |.||.....:||..      ||||.                   .:|..|:
  Rat    93 EQNLSGVCPGDPAKAAGAKEQRDSDLAAESNFRIYPWMR-------------------SSGTERK 138

  Fly   400 RGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAV---K 461
            ||||||||:||||||||||:|.|||||||||||||||||||||||||||||||.|||.:..   .
  Rat   139 RGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGT 203

  Fly   462 EINEQARRDREEQEK 476
            ...::|..|.||:|:
  Rat   204 TGQDKAEADEEEEEE 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	48/51 (94%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	6/24 (25%)
Hoxb7	NP_001017480.1	Antp-type hexapeptide	126..131		3/4 (75%)
		Homeobox	141..193	CDD:278475	48/51 (94%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..219		8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45659
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910