DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and ems

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_731868.1	Gene:	ems / 41697	FlyBaseID:	FBgn0000576	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	135/514 - (26%)
Similarity:	185/514 - (35%)	Gaps:	124/514 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNS 89
            :|...|...:||.|..:.........|:   .|...|..:|..|::|.:.    |.|.|......
  Fly     1 MTKMIPPVPTAAAAVMMPTPKQKIGFSI---ESIVGNDVSTAGGNSTPDL----SGPQSPPPGER 58

  Fly    90 NLNLSGGSLSPSHLSQHLGQSPH---SPVSSSSPFQQHHPQVQQQHLN----HQQ----QQHLHH 143
            |:..|.....|:.|:...|..||   :|.:...|:.  ||..|||||.    |..    |||:.|
  Fly    59 NVPGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYP--HPHAQQQHLQAPHPHPHLSPAQQHVLH 121

  Fly   144 Q----QQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTP----PSAGNSQAGD 200
            |    ||||.....|.....:|.|:.||     .||:|| |.:..|..|:|    |....|...:
  Fly   122 QHLLMQQQHPGTPKSHQDIQELLQRLHH-----NAAMAS-GLSPLQTRLSPETEQPQMAVSLKRE 180

  Fly   201 SSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSK----- 260
            .|.:|.......:...|....::|..:.:..|:..:||       .....||..|.|..:
  Fly   181 RSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSS-------PTLLISSPHATPPQQQQQQP 238

  Fly   261 ---------MYP---------------YVSNHPSSHGGLSGMAGFTGLED-KSCSRYTDTVMNSY 300
                     |:|               .|...|...||.....|..||.| |:...|
  Fly   239 PPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPY-------- 295

  Fly   301 QSMSVPASASAQF-------AQFYQHATAAASAV---SAASAGAIGVDSLGNACTQPASGVMPGA 355
              ::.|.....|.       |||...|...|..|   :||:|.|.|:       ...|:..||..
  Fly   296 --INAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGL-------PPHAAQFMPNP 351

  Fly   356 GGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRF---QTLELEKEF 417
            |.|..:    ...|||  |....|..|.....|.|..|   |.|:.::..|.|   |.|:||..|
  Fly   352 GMARDS----YQLYPW--LLSRHGRIFPHRFPGSFLVP---PFRKPKRIRTAFSPSQLLKLEHAF 407

  Fly   418 HFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEK 476
            ..|.|:....|..:|..|.|:|.|:|:||||||.|.|              |.::|.||
  Fly   408 ESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHK--------------RMQQEDEK 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/54 (43%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	4/21 (19%)
ems	NP_731868.1	Homeobox	392..444	CDD:278475	23/51 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I4196
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910