DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and exex

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	605	Identity:	146/605 - (24%)
Similarity:	212/605 - (35%)	Gaps:	210/605 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ISSHHLTTTPP-----NSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTNNSSS 79
            :||..::..||     .|||.::.:.|..:.....:| |.....::..|:..|......:|.|:.
  Fly     1 MSSAQVSQQPPPPPLTASSSTSMPSQLLLSHIQHHSS-SLHHQRSHQRSSPPAQDYDQGSNQSTL 64

  Fly    80 SPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSSSSP-FQQHHPQVQQQHLNHQQQQ---- 139
            ||      .|.:..|..:.||:|.:...|    ||||:.:| ......|...|..:.|..|
  Fly    65 SP------RSQITPSPPAASPTHSAATTG----SPVSTYTPALSPGGAQDSSQTESGQSSQMPLL 119

  Fly   140 -----------HLH----HQQ-------QQHH--HQYSSLSA------ALQLQQQQHHISKLAAA 174
                       |.|    |.:       ..||  |.:.:|..      .|.|......:...|||
  Fly   120 VAPMPVGTGPPHSHPPPPHPRLYVEGFPPPHHVPHPHPALGTYPLPRLPLMLPANPPGVPSGAAA 184

  Fly   175 -------AVASH----GHAHQQLLLTPPSAGNSQAGDSSC-----SPSPSASGS----------S 213
                   ..|:|    |.......|.||:  .||...|.|     :.|...||.          :
  Fly   185 PPPVSPQPAANHLSHSGATMATTTLLPPA--QSQPKKSFCIDALLAKSQHQSGEPQPIIVDDRLA 247

  Fly   214 SLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSF-AIPTSKMYPYVSNHPSSHGGLSG 277
            :||.:.:......|..:||.:||::.|||:||...:...:. .|..|:.|    :.||..|
  Fly   248 ALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISEQEALQRIRDSREY----DSPSPDG---- 304

  Fly   278 MAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGN 342
                       .|| :::..:|::| |.|.|...:..| ..|             ||:....|..
  Fly   305 -----------MSR-SESPTSSHRS-SPPISPGCEDQQ-QPH-------------GALHPQHLSM 342

  Fly   343 ACTQ----------PASGVMPGAGGAGGAGIADLPRY----PWMTLTDWMGSPFERVVCGDFNGP 393
            ..:.          |.|.:.|          .|.|.|    |:..|... ||.|.|.:     .|
  Fly   343 RMSDFHDEFKKPIPPHSPIRP----------QDFPLYAGGHPYQLLAQG-GSAFHRPL-----DP 391

  Fly   394 NGCP-------------------------------------------RRRGRQTYTRFQTLELEK 415
            :|.|                                           .||.|..:|..|.|||||
  Fly   392 SGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEK 456

  Fly   416 EFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQ 480
            :|..|.||:|.:|.|:|..|.|:|.|:||||||||||.|:..:|.:|..|:|:.:
  Fly   457 QFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKAN---------- 511

  Fly   481 ETMKSAQQNKQVQQQQQQQQ 500
                        ||||||||
  Fly   512 ------------QQQQQQQQ 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	30/51 (59%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	4/21 (19%)
exex	NP_648164.1	Homeobox	442..495	CDD:278475	30/52 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I4196
eggNOG	1	0.900	-	-		E2759_KOG0489
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810