DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and Rx

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_726006.3	Gene:	Rx / 37367	FlyBaseID:	FBgn0020617	Length:	904	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	107/505 - (21%)
Similarity:	172/505 - (34%)	Gaps:	151/505 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 NNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNL-----------------------SGGSL-- 98
            |.|.:...:|.|....::.|..||...::.::|..                       :||:|
  Fly   157 NRNGAANGSGRNPETVSDGSVDPSLGDDDATDLRCGMTLTQLRSMDNHMASMLQQHAKNGGALPY 221

  Fly    99 ----------------SPSHLSQHL-GQSPHSPVS--------SSSPFQQH-------------H 125
                            :|.|..|.: ||:.|:..:        ..:||..|             |
  Fly   222 GPPTPPGGQQPQVPNATPLHHGQQMGGQAGHATHAGHGHPTHHGHAPFGYHNAFGFGQGGHGYGH 286

  Fly   126 P-QVQQQHLNHQQQQHLHHQQQ-------------------QHHHQYSSLSAALQLQQQQHHISK 170
            | :....:||...|....:|.|                   .|....::|:|..|.||.||  ||
  Fly   287 PEEAAGNYLNSMHQMVEANQLQTGANGANPPPAPLPPSSFGSHQQHLAALAAQAQEQQNQH--SK 349

  Fly   171 LAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSP------SASGSSSLHRSLNDNSPGSASA 229
            .|.::....|..      .||.|...::..:..:||.      |.|.:|.|....:|      :|
  Fly   350 YAKSSPTGAGPP------PPPGAYFMESQTAPVAPSQINYDERSMSSASDLEEDDDD------AA 402

  Fly   230 SASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTD 294
            .......|....:.....||...|..:......|.::|     |.|.|  |..|:..:|......
  Fly   403 KLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLAN-----GQLPG--GNYGIRPRSMEEVHH 460

  Fly   295 TVMNSY---QSMSVPASASAQFAQFYQH---ATAAASAVSAASAGAIG------VDSLGN-ACTQ 346
            ...:.:   |..........|..|.:||   .:...:....:::|..|      .|||.| :|
  Fly   461 QQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSC-- 523

  Fly   347 PASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCG--DFNGPNGCPR---RRGRQTYT 406
                          |...||.:    |.:...|   |::..|  |....:.|.:   ||.|.|:|
  Fly   524 --------------ASSEDLNQ----TNSSEQG---EKITSGSDDEGQDDNCAKKKHRRNRTTFT 567

  Fly   407 RFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKE 456
            .:|..|||:.|..:||.....|.|:|..:.|.|.::::||||||.|.:::
  Fly   568 TYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQ 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	22/51 (43%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	0/1 (0%)
Rx	NP_726006.3	Homeobox	563..615	CDD:278475	22/51 (43%)
Rx	NP_726006.3	OAR	876..892	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I2937
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910