DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and Gsx2

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001131035.2	Gene:	Gsx2 / 364140	RGDID:	1308047	Length:	305	Species:	Rattus norvegicus

Alignment Length:	517	Identity:	118/517 - (22%)
Similarity:	167/517 - (32%)	Gaps:	240/517 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSK-FVFDSML--------PKYPQFQP----FISSHHLTTTPPNSSSAAVAAALAAAAASASASV 52
            ||: |..||::        |..|:..|    ||        |....|..|.:.......|..:..
  Rat     1 MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFFI--------PLGMPSPLVMSVSGPGCPSRKSGA 57

  Fly    53 ----SASSSSNNNSSNTIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQHLGQSPHS 113
                ....:|:.:||...||:....|..:.::            ::||.::....:..|.:|..|
  Rat    58 FCVCPLCVTSHLHSSRPPAGAGGGATGTAGAA------------VAGGGVAGGTGALPLLKSQFS 110

  Fly   114 PVSSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVAS 178
            |....:.|   .|:|  .|.:|      ||...||||               ||
  Rat   111 PGPGDAQF---CPRV--SHAHH------HHHAPQHHH---------------HH----------- 138

  Fly   179 HGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAA 243
              |..||                                      ||||:|:|:|      ||||
  Rat   139 --HQPQQ--------------------------------------PGSAAAAAAA------AAAA 157

  Fly   244 AAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPAS 308
            ||||||.                .||..|                                .|..
  Rat   158 AAAAAAL----------------GHPQHH--------------------------------APVC 174

  Fly   309 ASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMT 373
            |:..:                                                .::|..|:..:|
  Rat   175 AATTY------------------------------------------------NVSDPRRFHCLT 191

  Fly   374 LTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLT 438
            :.   ||...:|       |||   :|.|..:|..|.||||:||..|.||:|.||||||..|.|:
  Rat   192 MG---GSDTSQV-------PNG---KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLS 243

  Fly   439 ERQIKIWFQNRRMKLKKELR--------AVKEINEQARRDREEQEKMKAQETMKSAQQNKQV 492
            |:|:||||||||:|.|||.:        :.|.:..||...|.|.|...:.   .||.::|::
  Rat   244 EKQVKIWFQNRRVKHKKEGKGASRNNHASCKCVGSQAHYARSEDEDSLSP---ASANEDKEI 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	32/51 (63%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	7/29 (24%)
Gsx2	NP_001131035.2	Homeobox	207..260	CDD:395001	32/52 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810