DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and NOTO

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001127934.1	Gene:	NOTO / 344022	HGNCID:	31839	Length:	251	Species:	Homo sapiens

Alignment Length:	169	Identity:	51/169 - (30%)
Similarity:	69/169 - (40%)	Gaps:	47/169 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 GNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGS---------PFERV--VCG------ 388
            |:||..||..........||        .||...|.|:.:         |..||  |||
Human    70 GSACVHPAFWTAASLCATGG--------LPWACPTSWLPAYLSVGFYPVPGPRVAPVCGLLGFGV 126

  Fly   389 ------DFNG----PNGCP----------RRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAH 433
                  ..:|    |:..|          ::|.|..:...|..||||.|...|.|..::|.::|.
Human   127 TGLELAHCSGLWAFPDWAPTEDLQDTERQQKRVRTMFNLEQLEELEKVFAKQHNLVGKKRAQLAA 191

  Fly   434 ALCLTERQIKIWFQNRRMKLKKE--LRAVKEINEQARRD 470
            .|.|||.|:::||||||:|.:|:  |||.....|.|..|
Human   192 RLKLTENQVRVWFQNRRVKYQKQQKLRAAVTSAEAASLD 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/51 (45%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	6/17 (35%)
NOTO	NP_001127934.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..47
		Homeobox	160..211	CDD:278475	22/50 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	224..251		3/7 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910