Protein Alignment abd-A and HOXD3

DIOPT Version :10

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 77/253 - (30%)
• Similarity: 107/253 - (42%)
• Gaps: 65/253 - (25%)

  Fly   274 GLSGMAGFTGLEDKSCSRYTDTVMNS--YQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIG 336
            ||.|..|:        |:.|||...|  :|....||:||:....:...|.:..|:....:....|
Human    27 GLFGGYGY--------SKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKG 83

  Fly   337 VDSLGNACTQPASGVMPGAGGA------------------------------GGAGIADLPR--- 368
            .: |..:|.:|.:|...|.||.                              ||...|..|:
Human    84 AE-LNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGP 147

  Fly   369 -------------YPWMTLTDWMGSPFERVVCG------DFNGPNGCPRRRGRQTYTRFQTLELE 414
                         :|||  .:...:..::..|.      :...|.|...:|.|..||..|.:|||
Human   148 NASSSSATISKQIFPWM--KESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELE 210

  Fly   415 KEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDRE 472
            ||||||.||.|.||:|:|:.|.||||||||||||||||.||:.:|...::..|.:..|
Human   211 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPE 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	38/55 (69%)
		Abdominal-A	456..478	CDD:403567	3/17 (18%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		19/131 (15%)
		Antp-type hexapeptide	160..165		3/6 (50%)
		Homeodomain	195..251	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		3/16 (19%)
		DUF4074	369..430	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432