DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and HOXD1

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_078777.1	Gene:	HOXD1 / 3231	HGNCID:	5132	Length:	328	Species:	Homo sapiens

Alignment Length:	280	Identity:	84/280 - (30%)
Similarity:	114/280 - (40%)	Gaps:	49/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 GNSQAGDSSC--------SPSPSASGSSSLHRSLNDNSPGSAS---ASASASAASSVAAAAAAAA 247
            ||......||        ||||.|:.:       ..:.|..|:   |..:...|....||.||||
Human    44 GNGDGAFVSCLPLAAARPSPSPPAAPA-------RPSVPPPAAPQYAQCTLEGAYEPGAAPAAAA 101

  Fly   248 AAASSSFAIPTSKMYPYVSNHPS-SHGGLSGMAGFTGLEDKSCSRY-TDTVMNSYQSMSVPASAS 310
            ..|.          |.::.:.|: ...|:.|.|...|   .|...| |..|.:...|..:  |..
Human   102 GGAD----------YGFLGSGPAYDFPGVLGRAADDG---GSHVHYATSAVFSGGGSFLL--SGQ 151

  Fly   311 AQFAQFYQHATAAASAVSAASA--GAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMT 373
            ..:|.|.:.....|...::|..  ||....|       ||.|..|.:........|....:.||.
Human   152 VDYAAFGEPGPFPACLKASADGHPGAFQTAS-------PAPGTYPKSVSPASGLPAAFSTFEWMK 209

  Fly   374 LTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLT 438
            :   ..:..::....::...:  |....|..::..|..|||||||||.||||.||||||:.|.|.
Human   210 V---KRNASKKGKLAEYGAAS--PSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLN 269

  Fly   439 ERQIKIWFQNRRMKLKKELR 458
            :.|:||||||||||.||..|
Human   270 DTQVKIWFQNRRMKQKKRER 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	34/51 (67%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	1/3 (33%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		1/4 (25%)
		Homeobox	233..285	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810