DRSC/TRiP Functional Genomics Resources

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Protein Alignment abd-A and HOXC4

DIOPT Version :9

Sequence 1:NP_732176.1 Gene:abd-A / 42037 FlyBaseID:FBgn0000014 Length:590 Species:Drosophila melanogaster
Sequence 2:NP_055435.2 Gene:HOXC4 / 3221 HGNCID:5126 Length:264 Species:Homo sapiens


Alignment Length:337 Identity:95/337 - (28%)
Similarity:119/337 - (35%) Gaps:134/337 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 HAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAA 245
            |.||:|...||...:......||:   |..|            ||::.....|.|.         
Human    47 HHHQELYPPPPPRPSYPERQYSCT---SLQG------------PGNSRGHGPAQAG--------- 87

  Fly   246 AAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASAS 310
                                .:||                :||            ||:..||..|
Human    88 --------------------HHHP----------------EKS------------QSLCEPAPLS 104

  Fly   311 AQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPR------- 368
            .          |:||...|..           ||:|||               .|.|.       
Human   105 G----------ASASPSPAPP-----------ACSQPA---------------PDHPSSAASKQP 133

  Fly   369 --YPWMTLTDWMGSPFERVVCGDFN-GPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIE 430
              ||||          :::.....| ..||...:|.|..|||.|.||||||||:|.|||||||||
Human   134 IVYPWM----------KKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIE 188

  Fly   431 IAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQ 495
            |||:|||:||||||||||||||.||:.|...      .:.|.......|..|:.:|.........
Human   189 IAHSLCLSERQIKIWFQNRRMKWKKDHRLPN------TKVRSAPPAGAAPSTLSAATPGTSEDHS 247

  Fly   496 QQQQQQQQQQQQ 507
            |.....:||:.:
Human   248 QSATPPEQQRAE 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
abd-ANP_732176.1 Homeobox 402..454 CDD:278475 43/51 (84%)
Abdominal-A 456..478 CDD:289192 2/21 (10%)
HOXC4NP_055435.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..130 34/190 (18%)
Antp-type hexapeptide 135..140 4/14 (29%)
Homeobox 159..213 CDD:395001 43/53 (81%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 214..264 8/52 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.810

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