DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment abd-A and HOXB7

DIOPT Version :9

Sequence 1:NP_732176.1 Gene:abd-A / 42037 FlyBaseID:FBgn0000014 Length:590 Species:Drosophila melanogaster
Sequence 2:NP_004493.3 Gene:HOXB7 / 3217 HGNCID:5118 Length:217 Species:Homo sapiens


Alignment Length:290 Identity:103/290 - (35%)
Similarity:128/290 - (44%) Gaps:101/290 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 SSLH--RSLNDNSPGSASASASASAASSVAAAAAA------AAAAASSSFAIPTSKMYPYVSNHP 269
            |||:  .:|....|.|:|..|:.:.....:.|.|:      ..|.:.:|||.....:||      
Human     2 SSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYP------ 60

  Fly   270 SSHGGLSGM-------AGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAV 327
             ..||::|.       ||: |||                    |:|.:...|.|.|:        
Human    61 -GGGGMAGQSAAGVYAAGY-GLE--------------------PSSFNMHCAPFEQN-------- 95

  Fly   328 SAASAGAIGVDSLGNACTQPASGVMPG----AGGAGGAGIADLPR------YPWMTLTDWMGSPF 382
                                .|||.||    |.||.....:||..      ||||.         
Human    96 --------------------LSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMR--------- 131

  Fly   383 ERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQ 447
                      .:|..|:||||||||:||||||||||:|.||||||||||||.|||||||||||||
Human   132 ----------SSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQ 186

  Fly   448 NRRMKLKKELR-AVKEINEQARRDREEQEK 476
            |||||.|||.: |......|.|.:.||:|:
Human   187 NRRMKWKKENKTAGPGTTGQDRAEAEEEEE 216

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
abd-ANP_732176.1 Homeobox 402..454 CDD:278475 47/51 (92%)
Abdominal-A 456..478 CDD:289192 7/22 (32%)
HOXB7NP_004493.3 Antp-type hexapeptide 126..131 3/4 (75%)
Homeobox 141..193 CDD:278475 47/51 (92%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..217 8/23 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45659
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.910

Return to query results.
Submit another query.