Protein Alignment abd-A and HOXB4

DIOPT Version :10

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 86/269 - (31%)
• Similarity: 105/269 - (39%)
• Gaps: 64/269 - (23%)

  Fly   195 NSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAI--- 256
            ||...|....|....|.|..|.   :|:|||..:......::....|.....||.....:|.
Human     9 NSNYVDPKFPPCEEYSQSDYLP---SDHSPGYYAGGQRRESSFQPEAGFGRRAACTVQRYAACRD 70

  Fly   257 PTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHAT 321
            |.....|.....|....|||..|                        ..|..|.|...:..|...
Human    71 PGPPPPPPPPPPPPPPPGLSPRA------------------------PAPPPAGALLPEPGQRCE 111

  Fly   322 AAASA--VSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFER 384
            |.:|:  ....:...:......:||.:|..                   ||||          .:
Human   112 AVSSSPPPPPCAQNPLHPSPSHSACKEPVV-------------------YPWM----------RK 147

  Fly   385 VVCGDFNGPN--GCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQ 447
            |.....| ||  |...:|.|..|||.|.||||||||:|.|||||||:||||||||:|||||||||
Human   148 VHVSTVN-PNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQ 211

  Fly   448 NRRMKLKKE 456
            |||||.||:
Human   212 NRRMKWKKD 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	44/55 (80%)
		Abdominal-A	456..478	CDD:403567	0/1 (0%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		28/151 (19%)
		Antp-type hexapeptide	141..146		4/33 (12%)
		Homeodomain	163..219	CDD:459649	44/55 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		0/1 (0%)