Protein Alignment abd-A and HOXA2

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 93/318 - (29%)
• Similarity: 126/318 - (39%)
• Gaps: 86/318 - (27%)

  Fly   296 VMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGG--- 357
            |.:::||.|:..|.       ..|:|.........      :.||     .|.|....||||
Human    28 VADTFQSSSIKTST-------LSHSTLIPPPFEQT------IPSL-----NPGSHPRHGAGGRPK 74

  Fly   358 ---AGG------AGIADLPRYPWM-----------------TLTDWMGSPF-----ERVVCGDFN 391
               ||.      ||....|.||||                 ..|.....|.     |.:...|.:
Human    75 PSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGS 139

  Fly   392 GPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKE 456
            |...   ||.|..||..|.||||||||||.||.|.||:|||..|.|||||:|:||||||||.|::
Human   140 GGGS---RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201

  Fly   457 LRAVKEINEQAR-RDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDH 520
            .:..:..|.:.: :..|:.||::..|..|:..: :.:.......:::....||....|||.|..|
Human   202 TQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFE-QALSVSGALLEREGYTFQQNALSQQQAPNGH 265

  Fly   521 H--------SIIAHNPGHLHH------------SVVGQNDLKLGLGMGVGVGVGGIGP 558
            :        |.:..|..:|.|            |.:|||         .|.|:....|
Human   266 NGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQN---------CGAGLNNDSP 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	37/51 (73%)
		Abdominal-A	456..478	CDD:289192	4/22 (18%)
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		14/61 (23%)
		Antp-type hexapeptide	94..99		3/4 (75%)
		Homeobox	147..200	CDD:395001	37/52 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		6/30 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810