Protein Alignment abd-A and HHEX

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_002720.1
• Gene: HHEX / 3087
• HGNCID: 4901
• Length: 270
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 72/315 - (22%)
• Similarity: 111/315 - (35%)
• Gaps: 105/315 - (33%)

  Fly   246 AAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPA--- 307
            ||.|.......||..:.|   .||:..                   |.:.::....:...||
Human     9 AAGAVGVPLYAPTPLLQP---AHPTPF-------------------YIEDILGRGPAAPTPAPTL 51

  Fly   308 -SASAQFAQF-----------------YQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPG 354
             |.::.|...                 :.|.:|||.|.:.                        |
Human    52 PSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAY------------------------G 92

  Fly   355 AGGAGGAGIADLPRYPW-MTLTDWMGSPFERVVCGDFNGPNGCP-------------RRRGRQTY 405
            .||.||      |.||: .|:.|:..:...       :.|.|.|             |:.|:..:
Human    93 PGGFGG------PLYPFPRTVNDYTHALLR-------HDPLGKPLLWSPFLQRPLHKRKGGQVRF 144

  Fly   406 TRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRD 470
            :..||:||||:|....||:...|..:|..|.|:|||:|.||||||.|    .|.:|:.|.|:.:
Human   145 SNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAK----WRRLKQENPQSNK- 204

  Fly   471 REEQEKMKA---QETMKSAQQNKQVQQQQQQ---QQQQQQQQQQQHQQQQQQPQD 519
            :||.|.:.:   |.....::|||.......|   ....|:..:.:..:...|..|
Human   205 KEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEVD 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	24/51 (47%)
		Abdominal-A	456..478	CDD:289192	7/21 (33%)
HHEX	NP_002720.1	Interaction with SOX13. /evidence=ECO:0000269|PubMed:20028982	1..137		31/186 (17%)
		Required for WNT signaling induction. /evidence=ECO:0000269|PubMed:20028982	137..270		41/128 (32%)
		Homeobox	142..194	CDD:395001	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..270		14/67 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910