DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and dlx3b

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_571397.2	Gene:	dlx3b / 30585	ZFINID:	ZDB-GENE-980526-280	Length:	269	Species:	Danio rerio

Alignment Length:	344	Identity:	79/344 - (22%)
Similarity:	113/344 - (32%)	Gaps:	117/344 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 SPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPS 270
            |...|||.|.|.:..| ||             ::..::|......||......|..||...|  |
Zfish    14 STDLSGSMSCHPTSKD-SP-------------TLPESSATDMGYYSSHHEYYQSPPYPQQMN--S 62

  Fly   271 SHG-GLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQH-ATAAASAVSAASAG 333
            .|. .||||....|    :....|:...|:|:          |:..:.:. .|...|||.
Zfish    63 YHQFNLSGMGATPG----AYPTKTEYPYNTYR----------QYGHYNRDLQTPPQSAVK----- 108

  Fly   334 AIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPR 398
                       .:|.:.|                                |:|       ||.|:
Zfish   109 -----------EEPETEV--------------------------------RMV-------NGKPK 123

  Fly   399 --RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVK 461
              |:.|..|:.:|...|::.|....||....|.|:|..|.||:.|:||||||||.|.||..:
Zfish   124 KIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK--- 185

  Fly   462 EINEQARRDREEQEKMKAQETM---------------KSAQQNK-QVQQQQQQQQQQQQQQQQQH 510
              |.:...:...    .|.::|               .|:|.|: |:.|..........:....|
Zfish   186 --NGEVPLEHSP----NASDSMACNSPPSPAVWDNNAHSSQVNRGQIPQPPLSSTPPYMEDYSNH 244

  Fly   511 QQQQQQPQDHHSIIAHNPG 529
            ..||.....|.   .|:||
Zfish   245 WYQQGSHLQHP---VHHPG 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/51 (45%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	1/21 (5%)
dlx3b	NP_571397.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41		10/40 (25%)
		DLL_N	28..104	CDD:289198	22/105 (21%)
		Homeobox	128..181	CDD:278475	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..242		7/54 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..269		4/14 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910