DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and hoxd3a

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_571200.1	Gene:	hoxd3a / 30349	ZFINID:	ZDB-GENE-990415-120	Length:	396	Species:	Danio rerio

Alignment Length:	235	Identity:	77/235 - (32%)
Similarity:	102/235 - (43%)	Gaps:	45/235 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 AAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVM--------------- 297
            |.....::.|.|..|.|    ..:|.|.|..:.....:...|...|.:|.
Zfish    10 AGLFGGYSYPKSDSYTY----GPTHQGFSSSSIENDYQSPICPIQTTSVRQATHKNGDINGSCMR 70

  Fly   298 -NSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGA 361
             ::.|..|.|.|.|.|    .|.|..|||:.|.::          |:..:..|   |.:.|:..|
Zfish    71 PSASQGNSQPESISEQ----QQAAPLAASSPSPST----------NSTQKKKS---PSSNGSSTA 118

  Fly   362 -GIADLPRYPWMTLT------DWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHF 419
             .:.....:|||..|      .....|.....|.| ..|.|...:|.|..||..|.:||||||||
Zfish   119 TPVISKQIFPWMKETRQNAKQKSTNCPAAGETCDD-KSPPGPASKRVRTAYTSAQLVELEKEFHF 182

  Fly   420 NHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRA 459
            |.||.|.||:|:|:.|.||||||||||||||||.||:.::
Zfish   183 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKS 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	37/51 (73%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	0/4 (0%)
hoxd3a	NP_571200.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..163		36/166 (22%)
		Abdominal-A	116..237	CDD:332641	50/108 (46%)
		Antp-type hexapeptide	126..131		2/4 (50%)
		Homeobox	165..217	CDD:306543	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..246		0/4 (0%)
		DUF4074	333..394	CDD:315871
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810