DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abd-A and Hoxb3

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001100512.1	Gene:	Hoxb3 / 303488	RGDID:	1310780	Length:	429	Species:	Rattus norvegicus

Alignment Length:	325	Identity:	88/325 - (27%)
Similarity:	114/325 - (35%)	Gaps:	115/325 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 QQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGD 200
            |...||....|:......||..|     ..|..||....:....|.|.:. |..||.
  Rat    38 QAATHLEGDYQRSACSLQSLGNA-----APHAKSKELNGSCMRPGLAPEP-LPAPPG-------- 88

  Fly   201 SSCSPSPSASGSSSLHRSLNDNSPG-SASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPY 264
               ||.|||:.:|:...|.|...|. |......||:.|::                  |.:::|:
  Rat    89 ---SPPPSAAPTSTTSNSNNGGGPSKSGPPKCGASSNSTL------------------TKQIFPW 132

  Fly   265 VSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSA 329
            :..                      ||.|..:.||                    :...|.....
  Rat   133 MKE----------------------SRQTSKLKNS--------------------SPGTAEGCGG 155

  Fly   330 ASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPN 394
            ...|..|            .|...|.||:||.|                         ||.:.|.
  Rat   156 GGGGGGG------------GGSSSGGGGSGGGG-------------------------GDKSPPG 183

  Fly   395 GCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRA 459
            ....:|.|..||..|.:|||||||||.||.|.||:|:|:.|.|:||||||||||||||.||:.:|
  Rat   184 SAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKA 248

Fly 460 459
Rat 249 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	36/51 (71%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	1/4 (25%)
Hoxb3	NP_001100512.1	Homeobox	191..244	CDD:395001	36/52 (69%)
Hoxb3	NP_001100512.1	DUF4074	365..427	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810