Protein Alignment abd-A and GBX2

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001476.2
• Gene: GBX2 / 2637
• HGNCID: 4186
• Length: 348
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 85/338 - (25%)
• Similarity: 116/338 - (34%)
• Gaps: 87/338 - (25%)

  Fly   181 HAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASAS---ASASAASSVA-- 240
            |.|.|:...|         ...||   |.:...:|..:|....||..|||   ..|:||...|
Human    78 HPHHQIPSLP---------TGFCS---SLAQGMALTSTLMATLPGGFSASPQHQEAAAARKFAPQ 130

  Fly   241 ----------AAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDT 295
                      |.|..|.|.....|......:..: |...:....|.|.....|.::   |:..|.
Human   131 PLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAF-SAAETVQASLVGAVRGQGKDE---SKVEDD 191

  Fly   296 VMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNAC--TQPASGVMPGAGGA 358
            .....:|.|:.:...            .:|..:.....|...:..|:|.  |.|:||   .||..
Human   192 PKGKEESFSLESDVD------------YSSDDNLTGQAAHKEEDPGHALEETPPSSG---AAGST 241

  Fly   359 GGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYL 423
            ...|                                  ..||.|..:|..|.||||||||...||
Human   242 TSTG----------------------------------KNRRRRTAFTSEQLLELEKEFHCKKYL 272

  Fly   424 TRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQ 488
            :...|.:|||||.|:|.|:||||||||.|.|:    ||..|..::.. |.....|....:.....
Human   273 SLTERSQIAHALKLSEVQVKIWFQNRRAKWKR----VKAGNANSKTG-EPSRNPKIVVPIPVHVS 332

  Fly   489 NKQVQQQQQQQQQ 501
            ...::.|.||.:|
Human   333 RFAIRSQHQQLEQ 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	31/51 (61%)
		Abdominal-A	456..478	CDD:289192	4/21 (19%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..81		1/2 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..139		7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		18/123 (15%)
		Homeobox	250..303	CDD:306543	31/52 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810