DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and VAX2

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_036608.1	Gene:	VAX2 / 25806	HGNCID:	12661	Length:	290	Species:	Homo sapiens

Alignment Length:	185	Identity:	53/185 - (28%)
Similarity:	75/185 - (40%)	Gaps:	37/185 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 AAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAG--GAGIADLPRYPWMTLTDWMGSPFER 384
            :.|..:.|...|....:..|.:.:.||.....||...|  |.|.||..|               |
Human    29 SGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCR---------------R 78

  Fly   385 VVCGDFNG-------PNGCPRRRGRQTYTRF---QTLELEKEFHFNHYLTRRRRIEIAHALCLTE 439
            ::..|..|       |.|....|.::|.|.|   |...||.||....|:..|.|.|:|..|.|:|
Human    79 ILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSE 143

  Fly   440 RQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQVQQ 494
            .|:|:||||||.|.||:          ..||.|::....|.|...::...:.::|
Human   144 TQVKVWFQNRRTKQKKD----------QSRDLEKRASSSASEAFATSNILRLLEQ 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	25/54 (46%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	3/21 (14%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..75		12/45 (27%)
		Homeobox	105..158	CDD:306543	25/52 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	205..240
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910