Protein Alignment abd-A and EN2

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001418.2
• Gene: EN2 / 2020
• HGNCID: 3343
• Length: 333
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 77/317 - (24%)
• Similarity: 106/317 - (33%)
• Gaps: 100/317 - (31%)

  Fly   220 NDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSK----MYPYVSNHPSSH-------- 272
            ||..||.|:|:.........:....:.....||.....|.:    |.|.|...|.:|
Human     4 NDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHRITN 68

  Fly   273 -----------------------------GGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPAS 308
                                         ||..|..|.:|.|....:..::.::         .|
Human    69 FFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLL---------GS 124

  Fly   309 ASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACT--------------QPASGVMPGAGGAG 359
            .|.:..|....|..|...:.||.:.:.| |..|.:.|              .|..|.:...|..|
Human   125 GSREPRQNPPCAPGAGGPLPAAGSDSPG-DGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGG 188

  Fly   360 G------------AGIADLPRYPWMTLTDWMGSPFERVVCGDFNG-PNGCPR------------- 398
            |            || |:|...| |....|       |.|..::. |:..||
Human   189 GDLSVSSDSDSSQAG-ANLGAQP-MLWPAW-------VYCTRYSDRPSSGPRSRKPKKKNPNKED 244

  Fly   399 RRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKK 455
            :|.|..:|..|...|:.||..|.|||.:||..:|..|.|.|.||||||||:|.|:||
Human   245 KRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	26/51 (51%)
		Abdominal-A	456..478	CDD:289192	77/317 (24%)
EN2	NP_001418.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		9/44 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..206		25/121 (21%)
		homeobox domain	243..302		29/59 (49%)
		Homeobox	247..300	CDD:306543	26/52 (50%)
		Engrail_1_C_sig	302..331	CDD:313702	77/317 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910