DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and Phox2b

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_032914.1	Gene:	Phox2b / 18935	MGIID:	1100882	Length:	314	Species:	Mus musculus

Alignment Length:	292	Identity:	71/292 - (24%)
Similarity:	98/292 - (33%)	Gaps:	67/292 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 KSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGV 351
            :||....||        |..|||.|.|:...|.:....:.:........|..||
Mouse    15 ESCMAGMDT--------SSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPSL----------- 60

  Fly   352 MPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGC----PRRRGRQTYTRFQTLE 412
            .||:...|             ||.|...||:..|....|....|.    .:||.|.|:|..|..|
Mouse    61 TPGSCSLG-------------TLRDHQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKE 112

  Fly   413 LEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQEKM 477
            ||:.|...||.....|.|:|..:.|||.::::||||||.|.:|:.||.                .
Mouse   113 LERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAA----------------A 161

  Fly   478 KAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQ-QQQQQPQDHHSIIAHNPGHLHHSVVGQNDL 541
            .|....|:....|:....:..:.::.:....... .....|....|..|:..|
Mouse   162 AAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGG------------ 214

  Fly   542 KLGLGMGVGVGVGGIGPGIGGGLGGNLGMMSA 573
              |.|.......|..|||..||..|..|..:|
Mouse   215 --GGGPSPAGAPGAAGPGGPGGEPGKGGAAAA 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/51 (45%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	2/21 (10%)
Phox2b	NP_032914.1	Homeobox	102..155	CDD:395001	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..246		18/97 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910