Protein Alignment abd-A and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_659204.1
• Gene: Nkx6-1 / 18096
• MGIID: 1206039
• Length: 365
• Species: Mus musculus
• Alignment Length: 521
• Identity: 124/521 - (23%)
• Similarity: 180/521 - (34%)
• Gaps: 202/521 - (38%)

  Fly    11 PKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSNTIAGSNTSNTN 75
            |.||...|     .|.|.||:|||                                     |:::
Mouse    34 PLYPAAYP-----PLPTGPPSSSS-------------------------------------SSSS 56

  Fly    76 NSSSSPSSSSNNNSNLN-LSGGSLSPSHLSQHLGQSPHSPVSSSSPFQQHHPQVQQQHLNHQQQQ 139
            :||.||...|:|...|. .:.|.||                |..||.||
Mouse    57 SSSPSPPLGSHNPGGLKPPAAGGLS----------------SLGSPPQQ---------------- 89

  Fly   140 HLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCS 204
                           ||||     ..|.|:.                :|:.||   ......:..
Mouse    90 ---------------LSAA-----TPHGIND----------------ILSRPS---MPVASGAAL 115

  Fly   205 PSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHP 269
            ||.|.|||||           |:|:||||::||:.|||||||||||:||.|
Mouse   116 PSASPSGSSS-----------SSSSSASATSASAAAAAAAAAAAAAASSPA-------------- 155

  Fly   270 SSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGA 334
               |.|:|:..|:.|...                  |......|:.            |||:..|
Mouse   156 ---GLLAGLPRFSSLSPP------------------PPPPGLYFSP------------SAAAVAA 187

  Fly   335 IGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPW----MTLTDWMGSPFERVVCGDFNGPNG 395
            :|      ...:|.: .:||.......|:...|  ||    :..|...||     :..|.:|
Mouse   188 VG------RYPKPLA-ELPGRTPIFWPGVMQSP--PWRDARLACTPHQGS-----ILLDKDG--- 235

  Fly   396 CPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAV 460
             .|:..|.|::..|...|||.|....||....|..:|::|.:||.|:|:||||||.|.:|: .|.
Mouse   236 -KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK-HAA 298

  Fly   461 KEINEQARRDREEQEKMKAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHHSIIA 525
            :....:.::|.|       .|.:|...:|::......:........::..|..::......|::.
Mouse   299 EMATAKKKQDSE-------TERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSSGGSLLL 356

  Fly   526 H 526
            |
Mouse   357 H 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	23/51 (45%)
		Abdominal-A	456..478	CDD:289192	3/21 (14%)
Nkx6-1	NP_659204.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		49/224 (22%)
		Repressor domain. /evidence=ECO:0000250	102..269		68/245 (28%)
		Homeobox	240..293	CDD:278475	23/52 (44%)
		DUF3381	<291..345	CDD:288694	9/61 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		9/71 (13%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		8/58 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910