DRSC/TRiP Functional Genomics Resources

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Protein Alignment abd-A and Nkx2-2

DIOPT Version :9

Sequence 1:NP_732176.1 Gene:abd-A / 42037 FlyBaseID:FBgn0000014 Length:590 Species:Drosophila melanogaster
Sequence 2:NP_035049.1 Gene:Nkx2-2 / 18088 MGIID:97347 Length:273 Species:Mus musculus


Alignment Length:278 Identity:63/278 - (22%)
Similarity:97/278 - (34%) Gaps:79/278 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   269 PSSHGGLSGMAGFTGLEDKSC-SRYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASA 332
            |:...|..|......::.... |.:.|:..|.|...    .||.:..|:..|..||::....:|:
Mouse    41 PAKRAGPLGQGALDAVQSLPLKSPFYDSSDNPYTRW----LASTEGLQYSLHGLAASAPPQDSSS 101

  Fly   333 GAIGVDSLGNACTQPASGVMPG-----AGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNG 392
            .:          .:|::...|.     .||.|.||                              
Mouse   102 KS----------PEPSADESPDNDKETQGGGGDAG------------------------------ 126

  Fly   393 PNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKEL 457
                .:|:.|..:::.||.|||:.|....||:...|..:|..:.||..|:||||||.|.|:|: .
Mouse   127 ----KKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR-A 186

  Fly   458 RAVK--EINEQAR----------RDREEQEKMKAQE------------TMKSAQQNKQVQQQQQQ 498
            ||.|  |:.....          ||.:....:|||:            :..|||..:.:|...|.
Mouse   187 RAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQY 251

  Fly   499 QQQQQQQQQQQHQQQQQQ 516
            ......|....|...|.|
Mouse   252 SSASTPQYPTAHPLVQAQ 269

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
abd-ANP_732176.1 Homeobox 402..454 CDD:278475 22/51 (43%)
Abdominal-A 456..478 CDD:289192 6/33 (18%)
Nkx2-2NP_035049.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56 3/14 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..131 11/83 (13%)
Homeobox 131..185 CDD:395001 22/53 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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