Protein Alignment abd-A and DLX6

DIOPT Version :10

• Sequence 1: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 88/356 - (24%)
• Similarity: 111/356 - (31%)
• Gaps: 157/356 - (44%)

  Fly   116 SSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQ-----------HHHQYSSLSAALQLQQQQHHIS 169
            ||.|.|.:...|.|||   .||||....||||           |..|.|...|.........| |
Human    16 SSKSAFMEFGQQQQQQ---QQQQQQQQQQQQQPPPPPPPPPQPHSQQSSPAMAGAHYPLHCLH-S 76

  Fly   170 KLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASAS 234
            ..||||..||.|.|.|         :...|    ||..|..|:|..||||
Human    77 AAAAAAAGSHHHHHHQ---------HHHHG----SPYASGGGNSYNHRSL--------------- 113

  Fly   235 AASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNS 299
                          ||           |||:|:  |.|
Human   114 --------------AA-----------YPYMSH--SQH--------------------------- 124

  Fly   300 YQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIA 364
                       :.:.|.|.:::|||             .:.|:...|..:.|:..
Human   125 -----------SPYLQSYHNSSAAA-------------QTRGDDTDQQKTTVIEN---------- 155

  Fly   365 DLPRYPWMTLTDWMGSPFERVVCGD--FNGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRR 427
                                   |:  ||| .|...|:.|..|:..|...|...|....||....
Human   156 -----------------------GEIRFNG-KGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPE 196

  Fly   428 RIEIAHALCLTERQIKIWFQNRRMKLKKELR 458
            |.|:|.:|.||:.|:||||||:|.|.||.|:
Human   197 RAELAASLGLTQTQVKIWFQNKRSKFKKLLK 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	23/55 (42%)
		Abdominal-A	456..478	CDD:403567	1/3 (33%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	23/55 (42%)