DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and RHOXF1

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_011529583.1	Gene:	RHOXF1 / 158800	HGNCID:	29993	Length:	212	Species:	Homo sapiens

Alignment Length:	191	Identity:	56/191 - (29%)
Similarity:	77/191 - (40%)	Gaps:	32/191 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 DTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGV-----MP 353
            |||........|..|.:.|..       ||:||......||.|:  :||  ..|..||     |.
Human    36 DTVFYCLSVYQVKISPTPQLG-------AASSAEGHVGQGAPGL--MGN--MNPEGGVNHENGMN 89

  Fly   354 GAGG---AGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGP---NGCPRRRGRQTYTRFQTLE 412
            ..||   .||.|..:..:.|        ..|.|........||   |..||.| |..:|..|..|
Human    90 RDGGMIPEGGGGNQEPRQQP--------QPPPEEPAQAAMEGPQPENMQPRTR-RTKFTLLQVEE 145

  Fly   413 LEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREE 473
            ||..|....|.....|.|:|..|.:||.::::||:|:|.:.::..|.:...|| .|.|.::
Human   146 LESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANE-LRADPDD 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	18/51 (35%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	5/18 (28%)
RHOXF1	XP_011529583.1	homeodomain	132..190	CDD:238039	20/58 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910