DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and Hoxd3

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_034598.2	Gene:	Hoxd3 / 15434	MGIID:	96207	Length:	433	Species:	Mus musculus

Alignment Length:	254	Identity:	74/254 - (29%)
Similarity:	110/254 - (43%)	Gaps:	66/254 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 GLSGMAGFTGLEDKSCSRYTDTVMNS--YQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIG 336
            ||.|..|:        |:.|||...|  :|....||:|::..:.:...|.:..|:....:....|
Mouse    27 GLFGGYGY--------SKATDTYGYSTPHQPYPPPAAANSLDSDYPSSACSIQSSAPLRAPAHKG 83

  Fly   337 VDSLGNACTQPASGVMPGAGGAG------------------------------GAGI-------- 363
            .: |..:|.:|.:|...|.||..                              |:|:
Mouse    84 AE-LNGSCMRPGTGNSQGGGGGNQPPGLNSEQQPPQPPPPPPPTLPPSSPTNPGSGVPAKKTKGG 147

  Fly   364 -------ADLPR--YPWMTLTDWMGSPFERVVCG------DFNGPNGCPRRRGRQTYTRFQTLEL 413
                   :.:.:  :|||  .:...:..::..|.      :...|.|...:|.|..||..|.:||
Mouse   148 LSASSSSSTISKQIFPWM--KESRQNSKQKNSCATSGENCEDKSPPGPASKRVRTAYTSAQLVEL 210

  Fly   414 EKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDRE 472
            |||||||.||.|.||:|:|:.|.||||||||||||||||.||:.:|...::..|.:..|
Mouse   211 EKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAGQSPE 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	37/51 (73%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	3/17 (18%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..198		23/156 (15%)
		Antp-type hexapeptide	161..166		3/6 (50%)
		Homeobox	199..251	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..280		2/12 (17%)
		DUF4074	370..431	CDD:290032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810