DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and CPHXL

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001342542.1	Gene:	CPHXL / 105371346	HGNCID:	51815	Length:	405	Species:	Homo sapiens

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	60/180 - (33%)	Gaps:	69/180 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 SNTIAGSNTSNTNNSSSSPSSS----SNNNSNLNLSGGSLSPSHLSQHLGQSPHSPVSS------ 117
            |..:|..::.....:...|..:    .:..|..:.||.|.:...||.:..:..|.|.||
Human   200 SQQVASQSSYLVTGTEKHPGCAMGYGGDTGSGHSGSGHSTAYHFLSYNSAECLHPPPSSVPYFHG 264

  Fly   118 ----------SSPFQQHHPQ----VQQQH---------LNHQQQQ----HL-HHQQQQHH----- 149
                      :|||...:.|    |::.|         |..|||.    || .|||.|::
Human   265 ERTETKESQHASPFLLDYAQGAYGVKKDHCLCSFCLSLLGQQQQNDWQYHLQQHQQPQNYLEGMM 329

  Fly   150 ---------------HQYSSLSAALQLQ-----------QQQHHISKLAA 173
                           .|:||..:.||.|           |.||...::||
Human   330 LQEQLPMDSGPWDLGKQWSSAQSQLQSQLPQNNGKPLCSQLQHMSLQIAA 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192
CPHXL	NP_001342542.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
		HOX	28..82	CDD:197696
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..363		6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910