DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and Hoxa2

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_036713.2	Gene:	Hoxa2 / 103690123	RGDID:	2813	Length:	372	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	95/361 - (26%)
Similarity:	138/361 - (38%)	Gaps:	86/361 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 DNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLE 285
            ::.|..|....|....:....:::...:..|.|..||........|.:|.||...|..||.....
  Rat    13 NSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRQSAGAGGRPKS 77

  Fly   286 DKSCSRYTDTVMNSYQSMSVPASA--SAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPA 348
            ..:.||          ...|||.|  ..::....:...|..:|:..|:|      |.|.||....
  Rat    78 SPAGSR----------GSPVPARALQPPEYPWMKEKKAAKKTALPPAAA------STGPACLGHK 126

  Fly   349 SGVMPGAGGAGGAGIADLPRYPWMTLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLEL 413
            ..:....|..||:                                     ||.|..||..|.|||
  Rat   127 ESLEIADGSGGGS-------------------------------------RRLRTAYTNTQLLEL 154

  Fly   414 EKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQAR-RDREEQEKM 477
            |||||||.||.|.||:|||..|.|||||:|:||||||||.|::.:..:..|.:.: ::.|:.:|:
  Rat   155 EKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKV 219

  Fly   478 KAQETMKSAQQNKQVQQQQQQQQQQQQQQQQQHQQQQQQPQDHH--------SIIAHNPGHLHH- 533
            :..|..||..: :.:.......:::....||....|||.|..|:        |.:..|..:|.|
  Rat   220 EEDEEEKSLFE-QALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQTFPVSPLTSNEKNLKHF 283

  Fly   534 -----------SVVGQNDLKLGLGMGVGVGVGGIGP 558
                       |.:|||         .|.|:....|
  Rat   284 QHQSPTVPNCLSTMGQN---------CGAGLNNDSP 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	37/51 (73%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	3/22 (14%)
Hoxa2	NP_036713.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..96		17/63 (27%)
		Antp-type hexapeptide	96..101		0/4 (0%)
		Homeobox	143..196	CDD:395001	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..225		5/30 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910