DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and lmx1a

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_002934210.1	Gene:	lmx1a / 100492433	XenbaseID:	XB-GENE-481569	Length:	380	Species:	Xenopus tropicalis

Alignment Length:	210	Identity:	49/210 - (23%)
Similarity:	89/210 - (42%)	Gaps:	33/210 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 DFNGP-NGCPRRRGRQTYTRFQTLE---LEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNR 449
            |..|| :|..::|.::..|...|.:   .:..|..:....|:.|..:|....|:.|.:::||||:
Frog   179 DSKGPEDGKDQKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQ 243

  Fly   450 RMKLKKELRAVKEINEQARRDREEQEKMKAQETMKSAQQNKQ--------VQQQQQQQQQQQQQQ 506
            |.|:||..|  ::..:|.::|::...::.:.:|..|:..:.:        :.|||....:|....
Frog   244 RAKMKKLAR--RQQQQQQQQDQQNPSRIPSAQTHNSSSSSVEGIMNVFTTLPQQQLLSLEQNIYS 306

  Fly   507 QQQHQQ---QQQQPQDHHSIIAHNPG--HLHHSV----VGQNDLKLGLGMGVGVGVGGIGPGIGG 562
            ....||   ..|.|.||    .|..|  .|.|.:    ...|:|...|..|..:|      .|.|
Frog   307 ADPFQQGLTPPQMPGDH----MHPYGGESLFHDIDSDDASLNNLSECLLPGPELG------SIQG 361

  Fly   563 GLGGNLGMMSALDKS 577
            .:|..:..:.::..|
Frog   362 RVGNPIDRLYSMQNS 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	14/54 (26%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	3/21 (14%)
lmx1a	XP_002934210.1	LIM1_Lmx1a	35..86	CDD:188756
		LIM	94..148	CDD:351770
		Homeobox	195..249	CDD:365835	14/53 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910