DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and zfhx4

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_012820690.1	Gene:	zfhx4 / 100486096	XenbaseID:	XB-GENE-957673	Length:	3559	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	76/353 - (21%)
Similarity:	121/353 - (34%)	Gaps:	79/353 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 QQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSAGNSQAGDSSCSP----- 205
            |:......||.|..|:..:.:          .|.|.|.     ||.:|..:.:|..|.:|
Frog  2305 QEDSQNEDSLDATDQIMPKTY----------LSFGQAD-----TPKAAPTASSGSGSSTPLIPSP 2354

  Fly   206 -------SPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYP 263
                   ||.....|...:.::             :.|||:|:....:|:||||......|:..|
Frog  2355 RPEIDKISPKPDIPSEKPKQID-------------AIASSLASKLTQSASAASSDIQPSPSQQRP 2406

  Fly   264 YVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNS-------YQ-SMSVPASASAQFAQFYQHA 320
                 |...|..|..:..|.:..........::.||       || .....|..:.:..|.:||
Frog  2407 -----PQQIGRPSSASQTTSVPSSPLPISITSLQNSLPPQLLQYQCDQCTIAFPTLELWQEHQH- 2465

  Fly   321 TAAASAVSAASAGAIGVDSLGNACTQPASGVMPG----AGGAGGAGIADLPRYPWMTLTDWMGSP 381
                ....||....|....|......|.....|.    ||...|..:|.:|....|:..:...|.
Frog  2466 ----MHFLAAQNQFIHTQFLERPIDMPYMIFDPNNPLMAGQLLGGSVAHMPTQTGMSHANTSISL 2526

  Fly   382 FERVVCGDFNGPNGCPRRRG-------------RQTYTRFQTLELEKEFHFNHYLTRRRRIEIAH 433
            ..::   |....|.|..:.|             |.|.|..|...|.:::..:...||:....||.
Frog  2527 KRKL---DEKDENNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAR 2588

  Fly   434 ALCLTERQIKIWFQNRRMKLKK-ELRAV 460
            .:.|.:|.:::||||.|.:.:| :.||:
Frog  2589 EVGLKKRVVQVWFQNTRARERKGQFRAL 2616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	16/51 (31%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	2/5 (40%)
zfhx4	XP_012820690.1	C2H2 Zn finger	641..661	CDD:275368
		C2H2 Zn finger	696..713	CDD:275368
		C2H2 Zn finger	1372..1392	CDD:275371
		C2H2 Zn finger	1400..1421	CDD:275371
		C2H2 Zn finger	1516..1540	CDD:275368
		C2H2 Zn finger	1568..1586	CDD:275368
		HOX	2091..2146	CDD:197696
		Homeobox	2190..2244	CDD:365835
		COG5576	2527..2647	CDD:227863	23/93 (25%)
		Homeobox	2557..2610	CDD:365835	16/52 (31%)
		Homeobox	2880..2933	CDD:365835
		C2H2 Zn finger	3348..3390	CDD:275371
		C2H2 Zn finger	3392..3414	CDD:275371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910