DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abd-A and isl2

DIOPT Version :9

Sequence 1:	NP_732176.1	Gene:	abd-A / 42037	FlyBaseID:	FBgn0000014	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001159513.1	Gene:	isl2 / 100306962	XenbaseID:	XB-GENE-487556	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	136	Identity:	36/136 - (26%)
Similarity:	60/136 - (44%)	Gaps:	22/136 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 VVCG------DFNGPNGCPRRRGRQT--YTRFQTLELEKEFHF--NHYLTRRR-----RIEIAHA 434
            ::||      |...|:.......:||  .||.:|:..||:.|.  ..|....|     :.::...
Frog   137 LLCGAEHNLSDSGRPSSLRSHIHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEM 201

  Fly   435 LCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQE-----KMKAQETMK--SAQQNKQV 492
            ..|:.|.|::||||:|.|.||:...:|::.:|...|:...:     .|.|...::  ||.|...|
Frog   202 TGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQLNDKTSLQGLTGTPMVAGSPIRHDSAVQGSAV 266

  Fly   493 QQQQQQ 498
            :.|..|
Frog   267 EVQTYQ 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abd-A	NP_732176.1	Homeobox	402..454	CDD:278475	19/60 (32%)
abd-A	NP_732176.1	Abdominal-A	456..478	CDD:289192	3/26 (12%)
isl2	NP_001159513.1	LIM1_Isl	27..81	CDD:188752
		LIM2_Isl	89..143	CDD:188760	2/5 (40%)
		HOX	165..221	CDD:197696	17/55 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910