Protein Alignment Glut3 and HXT5

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 498
• Identity: 112/498 - (22%)
• Similarity: 193/498 - (38%)
• Gaps: 122/498 - (24%)

  Fly    64 FFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMVRL--LGCR-RTI 125
            |.|...||........:.|..:..:....:.:|...|..:..       ||||.:  :||. ..|
Yeast    95 FGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRT-------GLMVSIFNIGCAIGGI 152

  Fly   126 LIQLLPNF----LGWFLTVFARSVPML------------YAGRFFLGMCGGAHCVVVPIYNAEIS 174
            ::..|.:.    :|....|...|:.::            :.||...|:..|...|:.|:..:|:|
Yeast   153 VLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVS 217

  Fly   175 TTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVN-------LGL-------LALGPLQIL 225
            ..:.||.:...::.....|:...:..:...:    |:.|       |||       :.:|  ...
Yeast   218 PKQLRGTLVSCYQLMITFGIFLGYCTNFGTK----NYSNSVQWRVPLGLCFAWSIFMIVG--MTF 276

  Fly   226 MPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLT------RDPTESER---EVRQGPLLG 281
            :||||.|.|:.|.|..|:.||  .|..|  |..:...:|      :...|:||   ....|.|:.
Yeast   277 VPESPRYLVEVGKIEEAKRSL--ARANK--TTEDSPLVTLEMENYQSSIEAERLAGSASWGELVT 337

  Fly   282 FKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACFF--- 343
            .|.:..||:| ..:.|..||:|.|...|.:||..:...:.:...|...:.|| ::.|::.||
Yeast   338 GKPQMFRRTL-MGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLG-VVNFVSTFFSLY 400

  Fly   344 LVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSW----------------IALFCIA 392
            .|||.|||..|::...|::..       :.|:.::|:|.: |                |...|..
Yeast   401 TVDRFGRRNCLLWGCVGMICC-------YVVYASVGVTRL-WPNGQDQPSSKGAGNCMIVFACFY 457

  Fly   393 IFVGCYTAGVGSLTWVLNAELLVRPMRPL-----GCSIVCAFNWLTAFFVI-----------CWF 441
            ||  |:     :.||...|.:|:....||     ..||..|.||:..|.:.           .::
Yeast   458 IF--CF-----ATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYY 515

  Fly   442 GSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQ 484
            |        |:|:...:.|...:.|   ::||||.|:..::.:
Yeast   516 G--------YVFMGCMVFAYFYVFF---FVPETKGLTLEEVNE 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	111/490 (23%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	112/498 (22%)