Protein Alignment Glut3 and HXT1

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_011962.1
• Gene: HXT1 / 856494
• SGDID: S000001136
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 506
• Identity: 107/506 - (21%)
• Similarity: 193/506 - (38%)
• Gaps: 114/506 - (22%)

  Fly    50 GLYKATLYSNIGSFFFGIAVGW-SGT----------AERSVMEQHSYSFQPTELQWSGVCILLTL 103
            |:|.......:...|.|...|| :||          ..|..|:.|..|...::::...:..:..:
Yeast    60 GVYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNI 124

  Fly   104 GAALWCLPMGLMVRLLGCRRTILIQLLPNFLG----------WFLTVFARSVPMLYAGRFFLGMC 158
            |.|:..:.:..:..:.|.|..:::.::...:|          |:         ..:.||...|:.
Yeast   125 GCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWY---------QYFIGRIISGLG 180

  Fly   159 GGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVN-------LGL 216
            .|...|:.|:..:|::.::.||.:...::.....|:...:..:...:    |:.|       |||
Yeast   181 VGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTK----NYSNSVQWRVPLGL 241

  Fly   217 LALGPL-----QILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQ 276
            .....|     .:.:||||.|.|:.|.|..|..||..:.....| ...|.:.......|..|:|.
Yeast   242 CFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPD-HPYIQYELETIEASVEEMRA 305

  Fly   277 ------GPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLI 335
                  |.|...|....:|:: ..:.|..||:|.|...|.:||..:...:.:...|...:..|::
Yeast   306 AGTASWGELFTGKPAMFQRTM-MGIMIQSLQQLTGDNYFFYYGTIVFQAVGLSDSFETSIVFGVV 369

  Fly   336 LGFLAC--FFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSW------------- 385
            ..|..|  .:.|||.|||..|::.:.|:|..       :.|:.::|:|.: |
Yeast   370 NFFSTCCSLYTVDRFGRRNCLMWGAVGMVCC-------YVVYASVGVTRL-WPNGQDQPSSKGAG 426

  Fly   386 ---IALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPL----GC-SIVCAFNWLTAFFVI---- 438
               |...|..||  |:     :.||...|.:::....||    .| ||..|.||:..|.:.
Yeast   427 NCMIVFACFYIF--CF-----ATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTP 484

  Fly   439 -------CWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKI 482
                   .::|        |:|:...:.|...:.|   ::||||.||..::
Yeast   485 FITGAINFYYG--------YVFMGCMVFAYFYVFF---FVPETKGLSLEEV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	104/498 (21%)
HXT1	NP_011962.1	Sugar_tr	68..528	CDD:395036	105/498 (21%)