Protein Alignment Glut3 and HXT4

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 558
• Identity: 112/558 - (20%)
• Similarity: 214/558 - (38%)
• Gaps: 129/558 - (23%)

  Fly     9 AEPVEPPQSSRKSGTWFAKRPSEMPER---------HVERAPVRQKINNVGLYK--ATLYSNIG- 61
            |:.:.|.:|...|.   ...||...||         |.|      ..|.|.:.|  |:.|..:.
Yeast    18 ADALSPVESDSNSA---LSTPSNKAERDDMKDFDENHEE------SNNYVEIPKKPASAYVTVSI 73

  Fly    62 ----SFFFGIAVGW-SGT----------AERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLP 111
                ..|.|...|| :||          ..|..|:.|..::..::::...:..:..:|.|:..:.
Yeast    74 CCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGII 138

  Fly   112 MGLMVRLLGCRRTILIQLLPNFLG----------WFLTVFARSVPMLYAGRFFLGMCGGAHCVVV 166
            :..:..:.|.:..:::.::...:|          |:         ..:.||...|:..|...|:.
Yeast   139 LAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWY---------QYFIGRIISGLGVGGIAVLS 194

  Fly   167 PIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSL-------FLELRIINFVNLG----LLALG 220
            |:..:|:|....||.:...::.....|:...:..:.       .::.|:.  :.||    |..:|
Yeast   195 PMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVP--LGLGFAWALFMIG 257

  Fly   221 PLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYD---TRREIDFLTRDPTESER---EVRQGPL 279
            .: ..:||||.|.|:.|.|..|:.|:........|   ...|:: :.:...|:|:   ....|.:
Yeast   258 GM-TFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVE-VVQATVEAEKLAGNASWGEI 320

  Fly   280 LGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACF-- 342
            ...|.|..:| |.....|..||:|.|...|.:||..:...:.:...|...:.|| |:.|.:.|
Yeast   321 FSTKTKVFQR-LIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGLEDSFETSIVLG-IVNFASTFVG 383

  Fly   343 -FLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSW----------------IALFC 390
             |||:|.|||..|::.:|.:....:       |:.::|:|.: |                |...|
Yeast   384 IFLVERYGRRRCLLWGAASMTACMV-------VFASVGVTRL-WPNGKKNGSSKGAGNCMIVFTC 440

  Fly   391 IAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFF-----------VICWFGSH 444
            ..:|  |:......:.:|:|:|.....::....:|..|.||:..|.           :..::|
Yeast   441 FYLF--CFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYG-- 501

  Fly   445 GVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKI 482
                  |:|:...:.:...:.|   ::||||.|:..::
Yeast   502 ------YVFMGCLVFSYFYVFF---FVPETKGLTLEEV 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	99/500 (20%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	97/493 (20%)