Protein Alignment Glut3 and HXT14

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_014081.1
• Gene: HXT14 / 855398
• SGDID: S000005262
• Length: 540
• Species: Saccharomyces cerevisiae
• Alignment Length: 510
• Identity: 115/510 - (22%)
• Similarity: 200/510 - (39%)
• Gaps: 120/510 - (23%)

  Fly    56 LYSNIGSFFFGIAVGWSGTAERSVMEQHSY---------------SFQPTELQWS---------- 95
            |..::|.|.||..:|..|.....|..|..:               :.:.|:||..
Yeast    65 LVISLGGFIFGWDIGTIGGMTNMVSFQEKFGTTNIIHDDETIFVSTKKLTDLQIGLIISIFNISC 129

  Fly    96 --GVCILLTLG------AALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGR 152
              |...|..:|      ..:|   ..|:|..:|    |.||:|.....:|||:          ||
Yeast   130 GVGALTLSKIGDWIGRKGGIW---FALVVYCIG----ITIQILSYGRWYFLTL----------GR 177

  Fly   153 FFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFV----- 212
            ...|:..|...|:||::.:|.|..|.||:|...::.....|::..         .|:||:
Yeast   178 AVTGIGVGVTTVLVPMFLSENSPLKIRGSMVSTYQLIVTFGILMG---------NILNFICERCY 233

  Fly   213 -----NLG-----------LLALGPLQILMPESPAYYVDHGN-IPRAEDSLRFLRGQKYDTRREI 260
                 |:.           .:.:|...:.:||||.|.....| :|.|:.|...:.|........|
Yeast   234 KDPTQNIAWQLPLFLGYIWAIIIGMSLVYVPESPQYLAKIKNDVPSAKYSFARMNGIPATDSMVI 298

  Fly   261 DFL------TRDPTESEREVRQGPLL---GFKY----KKVRRSLARSLAIALLQKLCGALIFIFY 312
            :|:      ..:..|:..|.::..|:   .|::    .|:...|...:.|...|:|.|...|.:|
Yeast   299 EFIDDLLENNYNNEETNNESKKQSLVKRNTFEFIMGKPKLWLRLIIGMMIMAFQQLSGINYFFYY 363

  Fly   313 GLNMLDCLRIRREF--GLILC----LGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLH 371
            |.::...:.|:..:  .:||.    |..|||    .:.|::.|.:..|::.|..::|       :
Yeast   364 GTSVFKGVGIKDPYITSIILSSVNFLSTILG----IYYVEKWGHKTCLLYGSTNLLF-------Y 417

  Fly   372 FKVWMTMGL----TVMSWIALFCI-AIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSI-VCAF- 429
            ...:.|:|.    |..|.|.|..: ..|:..:...:|.:|:||.:||.  |:|....|: :|.|
Yeast   418 MMTYATVGTFGRETDFSNIVLIIVTCCFIFWFAITLGPVTFVLVSELF--PLRTRAISMAICTFI 480

  Fly   430 NWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQ 484
            ||:..|.:.........|....|..:||.....:::||.|.:|||:|.:..:|.:
Yeast   481 NWMFNFLISLLTPMIVSKIDFKLGYIFAACLLALIIFSWILVPETRKKNEQEINK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	114/502 (23%)
HXT14	NP_014081.1	MFS_HXT	62..537	CDD:340914	115/510 (23%)