DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and ATR1

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_013591.1	Gene:	ATR1 / 854924	SGDID:	S000004584	Length:	542	Species:	Saccharomyces cerevisiae

Alignment Length:	203	Identity:	43/203 - (21%)
Similarity:	70/203 - (34%)	Gaps:	73/203 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 ARSLAIALLQKLCGALIFI------FYGLNMLDCLRIRREFGLILCLGLILGFLA-----CFFLV 345
            ::|..:|....:.|:.|.|      .|||..:    :...:.|::...||.|...     .||::
Yeast   106 SKSWLMASFPLVSGSFILISGRLGDIYGLKKM----LLVGYVLVIIWSLICGITKYSGSDTFFII 166

  Fly   346 DRLGRRPLLIFSSAGIVFV---------SIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAG 401
            .|       .|...||.||         :||:|..|:..:.:.              |||.
Yeast   167 SR-------AFQGLGIAFVLPNVLGIIGNIYVGGTFRKNIVIS--------------FVGA---- 206

  Fly   402 VGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLF 466
                            |.|:|.::.|.|..|        .|:...|..|:.|..::|.|.:..:.
Yeast   207 ----------------MAPIGATLGCLFAGL--------IGTEDPKQWPWAFYAYSIAAFINFVL 247

  Fly   467 SLIYIPET 474
            |:..||.|
Yeast   248 SIYAIPST 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	43/203 (21%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392
ATR1	NP_013591.1	MFS_Amf1_MDR_like	73..517	CDD:341029	43/203 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900