Protein Alignment Glut3 and ITR2

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 468
• Identity: 100/468 - (21%)
• Similarity: 191/468 - (40%)
• Gaps: 53/468 - (11%)

  Fly    55 TLYSNIGSFFFGIAVGWSGTAERSV---MEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMV 116
            |..::|..|.||...|:..:|..|:   ::....::...||    :....:|||.:..:..|...
Yeast   113 TFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKEL----ITAATSLGALITSVGAGTAA 173

  Fly   117 RLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGA 181
            .:.|.|..::...|...:|..|.:.|.....:.|||..:|...|...::.|::.:||:....||.
Yeast   174 DVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGR 238

  Fly   182 MGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGPLQIL-----------MPESPAYYVD 235
            :.|:.......|.:.::.....|     |.|..|...|..|.::           :|::|.|||.
Yeast   239 LTVINSLWLTGGQLIAYGCGAGL-----NHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVM 298

  Fly   236 HGNIPRAEDSLRFLRGQKYDTRRE-IDFLTRDPTESEREV-RQGPLLGFKYKKVR---------R 289
            .|::.||:   ..|:....:|..| ||....:.:...:.: .:.|:..| :..|:         |
Yeast   299 KGDLKRAK---MVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKF-WNMVKELHTVPSNFR 359

  Fly   290 SLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGL-ILCLGLILGF-LACFFLVDRLGRRP 352
            :|.....:..:|:..|....:::...:.:.:..:....: |:..|....| |..||.:|::|||.
Yeast   360 ALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRY 424

  Fly   353 LLIFSSAGIVFVSI-------YLGLHFK----VWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLT 406
            :|:....|:....:       :||:.|.    |..:.|.:....:.:..|.::...|..|:|::.
Yeast   425 ILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVP 489

  Fly   407 WVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPY-LFLLFAIIASLILLFSLIY 470
            | ..:||..:.:|.:|.|...|.||..:..:...|.:......|. .|..||.:|.|..:|....
Yeast   490 W-QQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFC 553

  Fly   471 IPETKKLSSAKIQ 483
            .||...|...::|
Yeast   554 YPELSGLELEEVQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	98/461 (21%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	95/454 (21%)